NCT00094315

Brief Summary

To study of classical conditioning mechanisms associated with arousal, craving and cocaine use.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
16

participants targeted

Target at below P25 for phase_1

Timeline
Completed

Started Sep 2004

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2004

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

October 15, 2004

Completed
Same day until next milestone

First Posted

Study publicly available on registry

October 15, 2004

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2005

Completed
Last Updated

January 11, 2017

Status Verified

September 1, 2005

First QC Date

October 15, 2004

Last Update Submit

January 10, 2017

Conditions

Cocaine-Related Disorders

Outcome Measures

Primary Outcomes (2)

  • Stimulated and non-stimulated craving

  • Cocaine assessment

Interventions

Cocaine (IV)DRUG

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Be English-speaking volunteers who are cocaine dependent
  • Be non-treatment seeking at the time of the study
  • Meet DSM-IV criteria for cocaine dependence
  • Have ECG showing normal sinus rhythm, normal conductivity, and non clinically significant arrhythmias
  • Females must provide a negative pregnancy test and agree to use birth control
  • Have baseline laboratory tests within normal limits

You may not qualify if:

  • Please contact site for more information

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Texas Health Science Center

San Antonio, Texas, 78284, United States

Location

MeSH Terms

Conditions

Cocaine-Related Disorders

Interventions

Cocaine

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

TropanesAzabicyclo CompoundsAza CompoundsOrganic ChemicalsAlkaloidsHeterocyclic CompoundsBridged Bicyclo Compounds, HeterocyclicHeterocyclic Compounds, Bridged-Ring

Study Officials

  • John Roache, Ph.D.

    University of Texas

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Sponsor Type
NIH

Study Record Dates

First Submitted

October 15, 2004

First Posted

October 15, 2004

Study Start

September 1, 2004

Study Completion

July 1, 2005

Last Updated

January 11, 2017

Record last verified: 2005-09

Locations

US(1)