Event Related Potentials in Infants and Adults

NCT00088712 | Completed

• 2 other identifiers: 04025004-CH-0250
• Study Type: observational
• Target: 440
• Locations: 1 country
• Sites: 1

Brief Summary

This study will explore the development of visual perception and the brain activity that underlies it. It will examine electrical activity in the brain while people are processing characteristics of the visual environment, and how that processing might change with development. Infants who are within 2 weeks on either side of their 4-month birthday may be eligible for this study. A parent of the child also participates. Parents who join the study are asked basic questions about their family, such as its size and ethnic make-up, their infant's birth date, complications of pregnancy or delivery, and any health problems of the infant, such as congenital developmental disorders or visual abnormalities. Each family is seen at the clinic one time for a 45-minute visit. The infant is outfitted with an elastic net containing many small sensors that make contact with the scalp. He or she is then shown pictures on a computer screen. The sensors in the head net are connected to a computer that records the infant's brain activity while the infant watches the pictures on the screen. The head net is moistened with warm water before being applied, and is not uncomfortable to wear. Towels are available throughout the session to dry any excess moisture from the net.

Conditions

Healthy; Child Development

Keywords

Behavior and Neurocognition; Functional Brian Activity; Visual Perception; Selective Attention; Information Processing; Age Differences; Childhood Growth and Development; Cognitive Development; Brain Connectivity; Healthy Volunteer; HV

Outcome Measures

Primary Outcomes (1)

• EEG response

  Once following enrollment

Eligibility Criteria

• Age: 3 Months - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

Sponsors & Collaborators

• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): lead

Study Sites (1)

National Institutes of Health Clinical Center, 9000 Rockville Pike

Bethesda, Maryland, 20892, United States

Location

Related Publications (3)

• BERLYNE DE. The influence of the albedo and complexity of stimuli on visual fixation in the human infant. Br J Psychol. 1958 Nov;49(4):315-8. doi: 10.1111/j.2044-8295.1958.tb00669.x. No abstract available.

  PMID: 13596573 BACKGROUND

• Bornstein MH, Arterberry ME, Mash C. Differentiated brain activity in response to faces of "own" versus "unfamiliar" babies in primipara mothers: an electrophysiological study. Dev Neuropsychol. 2013;38(6):365-85. doi: 10.1080/87565641.2013.804923.

  PMID: 23971490 BACKGROUND

• Mash C, Bornstein MH, Arterberry ME. Brain dynamics in young infants' recognition of faces: EEG oscillatory activity in response to mother and stranger. Neuroreport. 2013 May 8;24(7):359-63. doi: 10.1097/WNR.0b013e32835f6828.

  PMID: 23470433 BACKGROUND

MeSH Terms

Conditions

Behavior

Study Officials

• Clay W. Mash, Ph.D.

  Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: NIH
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 30, 2004
• First Posted: August 2, 2004
• Study Start: July 28, 2004
• Study Completion: August 26, 2019
• Last Updated: September 10, 2019

Record last verified: 2019-08-26

Locations

US (1)