Effect of Respiratory Motion on Positron Emission Tomography Imaging
The Effects of Respiratory Motion on CT Based Attenuation Correction of Positron Emission Tomography Data: Liver and Heart Studies
2 other identifiers
observational
30
1 country
1
Brief Summary
This study will determine how breathing motions may affect positron emission tomography (PET) scans. It has been discovered that the quality of PET scans varies according to which part of the breathing cycle patients hold their breath. NIH Clinical Center patients 12 years of age and older who are scheduled to have PET and computed tomography (CT) scans as part of their standard medical care may be eligible for this study. Participants have their scheduled PET or CT scan as they normally would and are asked to hold their breath after breathing out, as is usual. In addition, for this study, patients are also asked hold their breath after breathing in and again at a point between breathing in and out. Each breath-hold is for around 15 seconds. The scans for each of the three different breath-holds are examined for differences. Some patients may also be asked to breathe through a tube called a pneumotachometer, or spirometer, to determine their normal breathing pattern. This involves breathing through a mouthpiece similar to a snorkel mouthpiece and takes about 2 minutes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Jul 2004
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2004
CompletedFirst Submitted
Initial submission to the registry
July 23, 2004
CompletedFirst Posted
Study publicly available on registry
July 26, 2004
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2006
CompletedMarch 4, 2008
June 1, 2006
July 23, 2004
March 3, 2008
Conditions
Keywords
Eligibility Criteria
You may qualify if:
- Up to 30 subjects will take part in the study, chosen from sequential incoming clinical patients who are scheduled for PET/CT studies of the torso and who have had or will have a diagnostic CT within one week of the PET/CT study, without regard to disease. The number of subjects selected for study per week will depend on patient load and availability of scanner and technologist). Approximately an equal number of males and females will be selected by alternating each selection between male and female. The selection of subjects asked to participate will be random, in the sense that whenever technologist and analysis time is available, the next subject scheduled for a whole body scan will be asked to participate.
You may not qualify if:
- Children under the age of 12.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Institutes of Health Clinical Center (CC)
Bethesda, Maryland, 20892, United States
Related Publications (1)
Osman MM, Cohade C, Nakamoto Y, Wahl RL. Respiratory motion artifacts on PET emission images obtained using CT attenuation correction on PET-CT. Eur J Nucl Med Mol Imaging. 2003 Apr;30(4):603-6. doi: 10.1007/s00259-002-1024-x. Epub 2003 Jan 21.
PMID: 12536242BACKGROUND
Study Design
- Study Type
- observational
- Sponsor Type
- NIH
Study Record Dates
First Submitted
July 23, 2004
First Posted
July 26, 2004
Study Start
July 1, 2004
Study Completion
June 1, 2006
Last Updated
March 4, 2008
Record last verified: 2006-06