Sponsor study identifier
Secondary identifiers
OTHER · Mayo Clinic Cancer Center
OTHER · Mayo Clinic IRB
interventional
N/A
1 country
19
Study Start
May 2003
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
September 2007
Actual (reported)Study Completion
Not reported
Date not reportedRATIONALE: Etanercept is a substance that is being studied as a treatment for cachexia (weight loss) and anorexia (lack of appetite) in patients who have cancer. It is not yet known whether etanercept is effective in improving cancer-related cachexia and anorexia. PURPOSE: Randomized phase III trial to determine the effectiveness of etanercept in treating cancer-related cachexia and anorexia in patients who have advanced cancer.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
Not reported
Date not reportedClick on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 3, 2002
Actual (reported)January 27, 2003
Actual (reported)May 2003
Date type not reportedThis date has not been verified as actual or estimated.
September 2007
Actual (reported)Comparison of weight gain and rate of weight change
Differences in appetite
Overall survival
Incidence of treatment-related toxicity
Comparison of quality of life (QOL) as assessed by the QOL UNISCALE and the Functional Assessment of Cancer Therapy-Anorexia/cachexia (FACT-An) scale at baseline, weekly for one month, and then monthly during study treatment
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
MBCCOP - Gulf Coast
Mobile, Alabama, 36607, United States
Mayo Clinic Scottsdale
Scottsdale, Arizona, 85259, United States
Mayo Clinic - Jacksonville
Jacksonville, Florida, 32224, United States
MBCCOP - Hawaii
Honolulu, Hawaii, 96813, United States
CCOP - Illinois Oncology Research Association
Peoria, Illinois, 61615-7828, United States
CCOP - Carle Cancer Center
Urbana, Illinois, 61801, United States
CCOP - Cedar Rapids Oncology Project
Cedar Rapids, Iowa, 52403-1206, United States
Jatoi A, Dakhil SR, Nguyen PL, Sloan JA, Kugler JW, Rowland KM Jr, Soori GS, Wender DB, Fitch TR, Novotny PJ, Loprinzi CL. A placebo-controlled double blind trial of etanercept for the cancer anorexia/weight loss syndrome: results from N00C1 from the North Central Cancer Treatment Group. Cancer. 2007 Sep 15;110(6):1396-403. doi: 10.1002/cncr.22944.
Jatoi A, Dakhil SR, Kugler JW, et al.: A placebo-controlled trial of etanercept, a tumor necrosis factor (TNF) inhibitor, in patients with the cancer anorexia/weight loss syndrome. North Central Cancer Treatment Group (NCCTG) trial N00C1. [Abstract] J Clin Oncol 24 (Suppl 18): A-8534, 476s, 2006.
Aminah Jatoi, MD
Mayo Clinic
First Submitted
October 3, 2002
First Posted
January 27, 2003
Study Start
May 2003
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
September 2007
Actual (reported)An Open-Label, Multicentre, Long-Term Extension Study of Etanercept in Ankylosing Spondylitis
Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.
CCOP - Iowa Oncology Research Association
Des Moines, Iowa, 50309-1854, United States
Siouxland Hematology-Oncology Associates at June E. Nylen Cancer Center
Sioux City, Iowa, 51101-1733, United States
CCOP - Wichita
Wichita, Kansas, 67214-3882, United States
CCOP - Michigan Cancer Research Consortium
Ann Arbor, Michigan, 48106, United States
Mayo Clinic Cancer Center
Rochester, Minnesota, 55905, United States
CCOP - Missouri Valley Cancer Consortium
Omaha, Nebraska, 68106, United States
Cancer Care Center at Medcenter One Hospital
Bismarck, North Dakota, 58501-5505, United States
CCOP - Oklahoma
Tulsa, Oklahoma, 74136, United States
CCOP - Geisinger Clinic and Medical Center
Danville, Pennsylvania, 17822-2001, United States
CCOP - Upstate Carolina
Spartanburg, South Carolina, 29303, United States
Rapid City Regional Hospital
Rapid City, South Dakota, 57709, United States
CCOP - Sioux Community Cancer Consortium
Sioux Falls, South Dakota, 57104, United States
Last Updated
May 5, 2011
Record last verified: 2011-05
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Source: ClinicalTrials.gov.
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