NCT00042445

Brief Summary

The aim of this study is to examine the association of exposure to air contaminants (PAH \& VOC) emitted from the petrochemical industries, specific genetic polymorphisms (P4501A1 (MspI \& exon 7) and GSTM1 \& T1) of study subjects and their parents, and the risks of brain tumors and leukemia among children and youths in metropolitan Kaohsiung, southern Taiwan.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,456

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2000

Longer than P75 for all trials

Geographic Reach
2 countries

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2000

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

July 30, 2002

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 1, 2002

Completed
2.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2005

Completed
Last Updated

September 4, 2006

Status Verified

September 1, 2006

First QC Date

July 30, 2002

Last Update Submit

September 1, 2006

Conditions

LeukemiaBrain Neoplasm

Keywords

NeoplasmPetrochemicalLeukemiaTaiwan

Eligibility Criteria

Age0 Years - 30 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Young population Less than 30 Resident of Kaohsiung metropolitan, Taiwan

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (2)

Harvard School of Public Health

Boston, Massachusetts, 02115, United States

Location

Kaohsiung Medical University

Kaohsiung City, 80708, Taiwan

Location

MeSH Terms

Conditions

LeukemiaBrain NeoplasmsNeoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Histologic TypeHematologic DiseasesHemic and Lymphatic DiseasesCentral Nervous System NeoplasmsNervous System NeoplasmsNeoplasms by SiteBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Sponsor Type
NIH

Study Record Dates

First Submitted

July 30, 2002

First Posted

August 1, 2002

Study Start

August 1, 2000

Study Completion

July 1, 2005

Last Updated

September 4, 2006

Record last verified: 2006-09

Locations

TW(1)US(1)