NCT00018187

Brief Summary

The purpose of this study is to test the effectiveness of a combination of the drugs bupropion and mecamylamine along with a nicotine patch as a therapy for smoking cessation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Nov 1998

Typical duration for phase_1

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 1998

Completed
2.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2001

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

July 3, 2001

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 5, 2001

Completed
Last Updated

January 21, 2009

Status Verified

May 1, 2007

First QC Date

July 3, 2001

Last Update Submit

January 20, 2009

Conditions

Smoking

Keywords

smoking cessationbupropionmecamylaminenicotine

Interventions

BupropionDRUG
MecamylamineDRUG
Nicotine PatchDRUG

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Subjects must be a smoker between 20 and 40 years old, have smoked at least 20 cigarettes per day for at least 2 years, wish to stop smoking and be in good general health

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

VA Greater Los Angeles Healthcare System

Los Angeles, California, 90073, United States

Location

MeSH Terms

Conditions

SmokingSmoking Cessation

Interventions

BupropionMecamylamineTobacco Use Cessation Devices

Condition Hierarchy (Ancestors)

BehaviorHealth Behavior

Intervention Hierarchy (Ancestors)

PropiophenonesKetonesOrganic ChemicalsNorbornanesBridged Bicyclo CompoundsBridged-Ring CompoundsHydrocarbons, CyclicHydrocarbonsPolycyclic CompoundsTherapeutics

Study Officials

  • Neil Hartman, M.D.

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
FED

Study Record Dates

First Submitted

July 3, 2001

First Posted

July 5, 2001

Study Start

November 1, 1998

Study Completion

June 1, 2001

Last Updated

January 21, 2009

Record last verified: 2007-05

Locations

US(1)