NCT00007384

Brief Summary

To longitudinally investigate multigenerational familial clustering of plasma low density lipoprotein cholesterol (LDL-C), with particular emphasis on the influences of apoE genotypes and various 'behaviors'.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Jul 2000

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2000

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

December 19, 2000

Completed
Same day until next milestone

First Posted

Study publicly available on registry

December 19, 2000

Completed
5.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2006

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2006

Completed
Last Updated

February 18, 2016

Status Verified

January 1, 2008

Enrollment Period

5.9 years

First QC Date

December 19, 2000

Last Update Submit

February 17, 2016

Conditions

Cardiovascular DiseasesAtherosclerosis

Eligibility Criteria

AgeUp to 100 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (3)

  • Miles MV, Horn PS, Tang PH, Morrison JA, Miles L, DeGrauw T, Pesce AJ. Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults. Clin Chim Acta. 2004 Sep;347(1-2):139-44. doi: 10.1016/j.cccn.2004.04.003.

    PMID: 15313151BACKGROUND

  • Miles MV, Morrison JA, Horn PS, Tang PH, Pesce AJ. Coenzyme Q10 changes are associated with metabolic syndrome. Clin Chim Acta. 2004 Jun;344(1-2):173-9. doi: 10.1016/j.cccn.2004.02.016.

    PMID: 15149886BACKGROUND

  • Miles MV, Horn PS, Morrison JA, Tang PH, DeGrauw T, Pesce AJ. Plasma coenzyme Q10 reference intervals, but not redox status, are affected by gender and race in self-reported healthy adults. Clin Chim Acta. 2003 Jun;332(1-2):123-32. doi: 10.1016/s0009-8981(03)00137-2.

    PMID: 12763289BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesAtherosclerosis

Condition Hierarchy (Ancestors)

ArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Officials

  • John Morrison

    Children's Hospital & Medical Center

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

December 19, 2000

First Posted

December 19, 2000

Study Start

July 1, 2000

Primary Completion

June 1, 2006

Study Completion

June 1, 2006

Last Updated

February 18, 2016

Record last verified: 2008-01