NCT00006511

Brief Summary

To identify gene variants in human chromosome 5Q31-33 that may be involved in the pathogenesis of asthma.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Sep 2000

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2000

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

November 20, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 21, 2000

Completed
4.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2005

Completed
Last Updated

February 18, 2016

Status Verified

January 1, 2006

First QC Date

November 20, 2000

Last Update Submit

February 17, 2016

Conditions

AsthmaLung Diseases

Eligibility Criteria

AgeUp to 100 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (6)

  • Martinez FD. Links between pediatric and adult asthma. J Allergy Clin Immunol. 2001 May;107(5 Suppl):S449-55. doi: 10.1067/mai.2001.114993.

    PMID: 11344374BACKGROUND

  • Martinez FD. The coming-of-age of the hygiene hypothesis. Respir Res. 2001;2(3):129-32. doi: 10.1186/rr48. Epub 2001 Apr 2.

    PMID: 11686875BACKGROUND

  • Patino CM, Martinez FD. Interactions between genes and environment in the development of asthma. Allergy. 2001 Apr;56(4):279-86. doi: 10.1034/j.1398-9995.2001.00135.x. No abstract available.

    PMID: 11284793BACKGROUND

  • LeVan TD, Von Essen S, Romberger DJ, Lambert GP, Martinez FD, Vasquez MM, Merchant JA. Polymorphisms in the CD14 gene associated with pulmonary function in farmers. Am J Respir Crit Care Med. 2005 Apr 1;171(7):773-9. doi: 10.1164/rccm.200404-530OC. Epub 2004 Dec 10.

    PMID: 15591473BACKGROUND

  • Martinez FD. Gene-environment interactions in asthma and allergies: a new paradigm to understand disease causation. Immunol Allergy Clin North Am. 2005 Nov;25(4):709-21. doi: 10.1016/j.iac.2005.09.001.

    PMID: 16257634BACKGROUND

  • Graves PE, Siroux V, Guerra S, Klimecki WT, Martinez FD. Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33. J Allergy Clin Immunol. 2005 Sep;116(3):650-6. doi: 10.1016/j.jaci.2005.05.004.

    PMID: 16159638BACKGROUND

MeSH Terms

Conditions

AsthmaLung Diseases

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • Fernando Martinez

    University of Arizona

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

November 20, 2000

First Posted

November 21, 2000

Study Start

September 1, 2000

Study Completion

August 1, 2005

Last Updated

February 18, 2016

Record last verified: 2006-01