NCT00006314

Brief Summary

To investigate the relationship between HCMV and bone marrow progenitor cells to understand whether HCMV is latent in CD34 + bone marrow progenitors and the mechanism by which the virus remains in a latent state.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Jul 1999

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 1999

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

September 28, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 29, 2000

Completed
3.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2004

Completed
Last Updated

May 13, 2016

Status Verified

January 1, 2006

First QC Date

September 28, 2000

Last Update Submit

May 12, 2016

Conditions

Blood DiseaseCytomegalovirus Infections

Eligibility Criteria

AgeUp to 100 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (4)

  • Crapnell K, Zanjani ED, Chaudhuri A, Ascensao JL, St Jeor S, Maciejewski JP. In vitro infection of megakaryocytes and their precursors by human cytomegalovirus. Blood. 2000 Jan 15;95(2):487-93.

    PMID: 10627453BACKGROUND

  • Rizvanov AA, van Geelen AG, Morzunov S, Otteson EW, Bohlman C, Pari GS, St Jeor SC. Generation of a recombinant cytomegalovirus for expression of a hantavirus glycoprotein. J Virol. 2003 Nov;77(22):12203-10. doi: 10.1128/jvi.77.22.12203-12210.2003.

    PMID: 14581557BACKGROUND

  • Khaiboullina SF, Maciejewski JP, Crapnell K, Spallone PA, Dean Stock A, Pari GS, Zanjani ED, Jeor SS. Human cytomegalovirus persists in myeloid progenitors and is passed to the myeloid progeny in a latent form. Br J Haematol. 2004 Aug;126(3):410-7. doi: 10.1111/j.1365-2141.2004.05056.x.

    PMID: 15257715BACKGROUND

  • Bego M, Maciejewski J, Khaiboullina S, Pari G, St Jeor S. Characterization of an antisense transcript spanning the UL81-82 locus of human cytomegalovirus. J Virol. 2005 Sep;79(17):11022-34. doi: 10.1128/JVI.79.17.11022-11034.2005.

    PMID: 16103153BACKGROUND

MeSH Terms

Conditions

Hematologic DiseasesCytomegalovirus Infections

Condition Hierarchy (Ancestors)

Hemic and Lymphatic DiseasesHerpesviridae InfectionsDNA Virus InfectionsVirus DiseasesInfections

Study Officials

  • Stephen St. Jeor

    University of Nevada, Las Vegas

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

September 28, 2000

First Posted

September 29, 2000

Study Start

July 1, 1999

Study Completion

June 1, 2004

Last Updated

May 13, 2016

Record last verified: 2006-01