NCT00006275

Brief Summary

OBJECTIVES: I. Determine the therapeutic efficacy and safety of topical calcitriol in children with psoriasis.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2000

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2000

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2000

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 11, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 12, 2000

Completed
Last Updated

June 24, 2005

Status Verified

September 1, 2000

First QC Date

September 11, 2000

Last Update Submit

June 23, 2005

Conditions

Psoriasis

Keywords

dermatologic disorderspsoriasisrare disease

Interventions

calcitriolDRUG

Eligibility Criteria

Age4 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- Diagnosis of psoriasis At least 2 lesions with area at least 30-50 cm2 --Prior/Concurrent Therapy-- No other concurrent therapy for psoriasis No concurrent calcium supplements greater than 1,000 mg/day No concurrent prednisone or other drugs affecting serum or urine calcium levels --Patient Characteristics-- Renal: No high blood or urinary calcium levels Other: Not pregnant Negative pregnancy test Fertile patients must use effective contraception

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

MeSH Terms

Conditions

PsoriasisSkin DiseasesRare Diseases

Interventions

Calcitriol

Condition Hierarchy (Ancestors)

Skin Diseases, PapulosquamousSkin and Connective Tissue DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

DihydroxycholecalciferolsHydroxycholecalciferolsCholecalciferolCholestenesCholestanesSteroidsFused-Ring CompoundsPolycyclic CompoundsSterolsVitamin DSecosteroidsMembrane LipidsLipids

Study Officials

  • Michael F. Holick

    Boston University

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Purpose
TREATMENT
Sponsor Type
NIH

Study Record Dates

First Submitted

September 11, 2000

First Posted

September 12, 2000

Study Start

July 1, 2000

Study Completion

July 1, 2000

Last Updated

June 24, 2005

Record last verified: 2000-09