NCT00005920

Brief Summary

The purpose of this study is to see if it is safe and effective to give L-743,872 to patients with thrush, an AIDS-related yeast infection of the mouth, that has not been cured with fluconazole treatment.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for phase_2

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 19, 2000

Completed
1.2 years until next milestone

First Posted

Study publicly available on registry

August 31, 2001

Completed
Last Updated

June 24, 2005

Status Verified

June 1, 2000

First QC Date

June 19, 2000

Last Update Submit

June 23, 2005

Conditions

Keywords

AIDS-Related Opportunistic InfectionsDose-Response Relationship, DrugFluconazoleAntifungal AgentsCandidiasis, OralPharyngeal DiseasesMK 0991

Interventions

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • You may be eligible for this study if you:
  • Have thrush that has not responded to fluconazole treatment.
  • Are 18-65 years old.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Carol Sable

Rahway, New Jersey, 07065, United States

Location

MeSH Terms

Conditions

Candidiasis, OralHIV InfectionsAIDS-Related Opportunistic InfectionsPharyngeal Diseases

Interventions

Caspofungin

Condition Hierarchy (Ancestors)

CandidiasisMycosesBacterial Infections and MycosesInfectionsMouth DiseasesStomatognathic DiseasesBlood-Borne InfectionsCommunicable DiseasesSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System DiseasesOpportunistic InfectionsOtorhinolaryngologic Diseases

Intervention Hierarchy (Ancestors)

LipopeptidesLipidsPeptidesAmino Acids, Peptides, and ProteinsEchinocandinsPeptides, Cyclic

Study Design

Study Type
interventional
Phase
phase 2
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

June 19, 2000

First Posted

August 31, 2001

Last Updated

June 24, 2005

Record last verified: 2000-06

Locations