NCT00004375

Brief Summary

OBJECTIVES: I. Evaluate the mechanisms of ultraviolet A-1 light therapy in patients with systemic lupus erythematosus and normal controls.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for phase_2

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 1991

Completed
8.1 years until next milestone

First Submitted

Initial submission to the registry

October 18, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 19, 1999

Completed
Last Updated

June 24, 2005

Status Verified

January 1, 2004

First QC Date

October 18, 1999

Last Update Submit

June 23, 2005

Conditions

Systemic Lupus Erythematosus

Keywords

arthritis & connective tissue diseasesimmunologic disorders and infectious disordersrare diseasesystemic lupus erythematosus

Interventions

ultraviolet A-1 light treatmentPROCEDURE

Eligibility Criteria

Age15 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- Patients ages 15 to 70 with symptomatic systemic lupus erythematosus meeting American Rheumatism Association criteria and normal controls --Prior/Concurrent Therapy-- No requirement for tetracycline or other photosensitizing drugs

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (2)

General Clinical Research Center and Charity Hospital (University of Louisiana)

New Orleans, Louisiana, 70112-2822, United States

RECRUITING

Alton Ochsner Medical Foundation Hospital

New Orleans, Louisiana, 70121, United States

RECRUITING

Related Publications (1)

  • McGrath H, Martinez-Osuna P, Lee FA. Ultraviolet-A1 (340-400 nm) irradiation therapy in systemic lupus erythematosus. Lupus. 1996 Aug;5(4):269-74. doi: 10.1177/096120339600500405.

    PMID: 8869897BACKGROUND

MeSH Terms

Conditions

Lupus Erythematosus, SystemicArthritisConnective Tissue DiseasesImmune System DiseasesCommunicable DiseasesRare Diseases

Condition Hierarchy (Ancestors)

Skin and Connective Tissue DiseasesAutoimmune DiseasesJoint DiseasesMusculoskeletal DiseasesInfectionsDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Hugh McGrath, Jr.

    Louisiana State University Health Sciences Center in New Orleans

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
phase 2
Purpose
TREATMENT
Sponsor Type
NIH

Study Record Dates

First Submitted

October 18, 1999

First Posted

October 19, 1999

Study Start

September 1, 1991

Last Updated

June 24, 2005

Record last verified: 2004-01

Locations

US(2)