Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis
Effects of Diet and Medication in Patients With Cerebrotendinous Xanthomatosis (CTX)
Effects of Diet and Medication in Patients With Cerebrotendinous Xanthomatosis (CTX)
Sponsor study identifier
Secondary identifiers
interventional
5
1 country
1
Study Start
January 1996
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
Not reported
Date not reportedOBJECTIVES: I. Assess the biosynthesis of cholesterol and cholestanol, and measure the turnover of individual sterols and bile acids in patients with cerebrotendinous xanthomatosis before and after a cholesterol- and cholestanol-free diet. II. Assess the biosynthesis of cholesterol and cholestanol, and measure the turnover of individual sterols and bile acids in these patients before and after lovastatin and chenodeoxycholic acid.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
Not reported
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 1996
Date type not reportedThis date has not been verified as actual or estimated.
October 18, 1999
Actual (reported)October 19, 1999
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Oregon Health and Science University
Portland, Oregon, 97239-3098, United States
William Connor
Oregon Health and Science University
First Submitted
October 18, 1999
First Posted
October 19, 1999
Study Start
January 1996
Date type not reportedThis date has not been verified as actual or estimated.
Last Updated
June 24, 2005
Record last verified: 2003-12
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Source: ClinicalTrials.gov.
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