A Study of the Safety and Effectiveness of Different Doses of 1592U89 in HIV-Infected Patients
A Phase II Randomized, Blinded, Dose-Ranging Multicenter Study to Evaluate the Safety and Efficacy of Different Regimens of 1592U89 Monotherapy Upon Selected Immunological and Virological Markers of HIV-1 Infection in Antiretroviral Therapy-Naive Patients
2 other identifiers
interventional
N/A
2 countries
6
Brief Summary
The purpose of this study is to see if giving 1592U89 to HIV-infected patients is safe and effective in lowering viral load (level of HIV in the blood) and raising the level of CD4 cells (cells of the body that help fight infection).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
6 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 2, 1999
CompletedFirst Posted
Study publicly available on registry
August 31, 2001
CompletedJune 24, 2005
August 1, 1997
November 2, 1999
June 23, 2005
Conditions
Interventions
Sponsors & Collaborators
- Glaxo Wellcomelead
Study Sites (6)
Group Hospier Pitie-Salpetriere / Maladies Infec et Trop
Paris, France
Groupe Hospitalier Bichat-Claude Bernard
Paris, France
Hopital de Purpan / CHU de Rangueil / Medecine Interue
Toulouse, France
Hopital de Purpan / Service du Professeur Auvergnat
Toulouse, France
Universitat Erlangen
Erlangen, Germany
Universitatsklinikurn Frankfurt
Frankfurt, Germany
Related Publications (1)
Staszewski S, Katlama C, Harrer T, Massip P, Yeni P, Cutrell A, Tortell SM, Harrigan RP, Steel H, Lanier RE, Pearce G. A dose-ranging study to evaluate the safety and efficacy of abacavir alone or in combination with zidovudine and lamivudine in antiretroviral treatment-naive subjects. AIDS. 1998 Nov 12;12(16):F197-202. doi: 10.1097/00002030-199816000-00001.
PMID: 9833847BACKGROUND