The Therakos UVAR Photopheresis System in the Treatment of AIDS-Related Complex

You may not qualify if:

• Co-existing Condition:
• Patients with the following conditions or symptoms are excluded:
• Inability to tolerate extracorporeal volume loss during the leukocyte-enrichment phase.
• Photosensitive disease, such as porphyria or systemic lupus erythematosus. Care must be taken in selecting patients who require drugs (either systemically or topically) during the course of the study with photosensitizing potential such as phenothiazines, tetracyclines, sulfonamides or chlorothiazide.
• Renal insufficiency with creatinine \> 3 mg/dl.
• Symptoms of toxic effects (World Health Organization Criteria) resulting from previous therapy.
• Severe emotional, behavioral or psychiatric problems that in the opinion of the investigator would result in poor compliance with the treatment regimen.
• Idiosyncratic or hypersensitivity reactions to 8-MOP compounds.
• History of or active Pneumocystis carinii pneumonia, other opportunistic infection or neoplasms (Kaposi's sarcoma), or wasting syndrome.
• Active hepatitis.
• Aphakia because of the significantly increased risk of retinal damage due to absence of lenses.
• Concurrent Medication:
• Excluded:
• Zidovudine (AZT).
• Photosensitizing drugs should not be administered prior to photopheresis treatment.
• +16 more criteria