NCT00001292|Completed
Study of Scaling Disorders and Other Inherited Skin Diseases
Clinical and Genetic Studies of the Scaling Disorders and Other Selected Genodermatoses
Loading search results
Clinical and Genetic Studies of the Scaling Disorders and Other Selected Genodermatoses
Sponsor study identifier
Secondary identifiers
observational
N/A
1 country
1
Study Start
February 1992
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
April 2001
Date type not reportedThis date has not been verified as actual or estimated.
The purpose of this study is to identify the genes responsible for certain scaling disorders and other inherited skin diseases and to learn about the medical problems they cause. In some cases, these may include problems affecting organs other than the skin, such as the eyes, teeth and bones. Patients with inherited skin disorders, including Darier's disease (keratosis follicularis), lamellar ichthyosis, epidermolysis bullosa, cystic acne, and others, and their relatives may be eligible for this study. Patients will have a medical history, physical examination with particular emphasis on the skin, and routine blood tests. Additional procedures for patients and unaffected relatives may include:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 2001
Date type not reportedThis date has not been verified as actual or estimated.
Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 1992
Date type not reportedThis date has not been verified as actual or estimated.
November 3, 1999
Actual (reported)April 2001
Date type not reportedThis date has not been verified as actual or estimated.
December 10, 2002
Actual (reported)Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.
National Cancer Institute (NCI)
Bethesda, Maryland, 20892, United States
DiGiovanna JJ, Bale SJ. Epidermolytic hyperkeratosis: applied molecular genetics. J Invest Dermatol. 1994 Mar;102(3):390-4. doi: 10.1111/1523-1747.ep12371801.
Russell LJ, DiGiovanna JJ, Rogers GR, Steinert PM, Hashem N, Compton JG, Bale SJ. Mutations in the gene for transglutaminase 1 in autosomal recessive lamellar ichthyosis. Nat Genet. 1995 Mar;9(3):279-83. doi: 10.1038/ng0395-279.
First Submitted
November 3, 1999
First Posted
December 10, 2002
Study Start
February 1992
Date type not reportedThis date has not been verified as actual or estimated.
Study Completion
April 2001
Date type not reportedThis date has not been verified as actual or estimated.
Last Updated
March 5, 2008
Record last verified: 2000-04
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: