Study Stopped
due to lack of enrollment
Training Levels Comparison Trial
Training Levels Comparison (TLC) Trial in Patients With Coronary Heart Disease
2 other identifiers
observational
N/A
0 countries
N/A
Brief Summary
To determine the effects of high or low intensity long-term exercise conditioning in patients with coronary artery disease.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
Started Dec 1986
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 1986
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 1991
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 1991
CompletedFirst Submitted
Initial submission to the registry
October 27, 1999
CompletedFirst Posted
Study publicly available on registry
October 28, 1999
CompletedJanuary 6, 2016
November 1, 2013
4.2 years
October 27, 1999
January 5, 2016
Conditions
Study Arms (2)
Low intensity exercise
High intensity exercise
Interventions
Eligibility Criteria
Men between the ages of 30 and 67 who respond to an advertisement for research participants.
Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.
Sponsors & Collaborators
Related Publications (4)
Lee JY, Oberman A, Fletcher GF, Raczynski JM, Fletcher BJ, Nanda NC, Jensen BE. Design of the training levels comparison trial. Control Clin Trials. 1994 Feb;15(1):59-76. doi: 10.1016/0197-2456(94)90028-0.
PMID: 8149771BACKGROUNDKim JR, Oberman A, Fletcher GF, Lee JY. Effect of exercise intensity and frequency on lipid levels in men with coronary heart disease: Training Level Comparison Trial. Am J Cardiol. 2001 Apr 15;87(8):942-6; A3. doi: 10.1016/s0002-9149(01)01425-4.
PMID: 11305982BACKGROUNDJensen BE, Fletcher BJ, Rupp JC, Fletcher GF, Lee JY, Oberman A. Training level comparison study. Effect of high and low intensity exercise on ventilatory threshold in men with coronary artery disease. J Cardiopulm Rehabil. 1996 Jul-Aug;16(4):227-32. doi: 10.1097/00008483-199607000-00003.
PMID: 8872288BACKGROUNDLee JY, Jensen BE, Oberman A, Fletcher GF, Fletcher BJ, Raczynski JM. Adherence in the training levels comparison trial. Med Sci Sports Exerc. 1996 Jan;28(1):47-52. doi: 10.1097/00005768-199601000-00013.
PMID: 8775354BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Albert Oberman
University of Alabama at Birmingham
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 27, 1999
First Posted
October 28, 1999
Study Start
December 1, 1986
Primary Completion
March 1, 1991
Study Completion
March 1, 1991
Last Updated
January 6, 2016
Record last verified: 2013-11