NCT00000386

Brief Summary

The purpose of this study is to evaluate a behavioral treatment program for children and adolescents with OCD and their families. Exposure and Response Prevention (ERP) behavior therapy, in which the patient is gradually exposed to the object or situation that causes anxiety and is taught to refrain from responding in a compulsive manner, is combined with family counseling (Family Treatment Program). This treatment will be compared to Relaxation Training (RT). OCD is a long-term, often disabling disorder that can cause significant family disruption. ERP is a promising treatment for children with OCD, and it is thought that family participation (through the Family Treatment Program) may be a helpful addition. RT is a common treatment for anxiety. Patients are assigned randomly (like tossing a coin) to receive either the ERP/Family Treatment Program or RT. Both treatments will be delivered over 12 90-minute outpatient sessions to youngsters and their families. All participants (patients and family members) will be assessed for treatment response each month during treatment, after treatment is finished, and then at 2 follow-up visits over the following 6 months. A child/adolescent may be eligible for this study if he/she: Has obsessive-compulsive disorder (OCD), is medication-free, and is 8 to 17 years old.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Dec 1998

Longer than P75 for phase_3

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 1998

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

November 2, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 3, 1999

Completed
4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2003

Completed
Last Updated

February 12, 2008

Status Verified

February 1, 2008

First QC Date

November 2, 1999

Last Update Submit

February 8, 2008

Conditions

Keywords

AdolescenceChildComparative StudyFamilyFemaleHumanMaleObsessive-Compulsive DisorderRelaxation TechniquesObsessive-Compulsive Disorder -- *therapy

Interventions

Eligibility Criteria

Age8 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Patients must have:
  • Obsessive-compulsive disorder for which he/she has not received medication.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Univ. of California / Los Angeles / Neuropsychiatric Inst.

Los Angeles, California, 90024-1759, United States

Location

Related Publications (2)

  • Kircanski K, Wu M, Piacentini J. Reduction of subjective distress in CBT for childhood OCD: nature of change, predictors, and relation to treatment outcome. J Anxiety Disord. 2014 Mar;28(2):125-32. doi: 10.1016/j.janxdis.2013.05.004. Epub 2013 May 21.

  • Piacentini J, Bergman RL, Chang S, Langley A, Peris T, Wood JJ, McCracken J. Controlled comparison of family cognitive behavioral therapy and psychoeducation/relaxation training for child obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry. 2011 Nov;50(11):1149-61. doi: 10.1016/j.jaac.2011.08.003. Epub 2011 Sep 22.

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Interventions

Relaxation TherapyBehavior TherapyFamily Therapy

Condition Hierarchy (Ancestors)

Anxiety DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsPsychotherapyBehavioral Disciplines and ActivitiesPsychotherapy, GroupSocioenvironmental Therapy

Study Officials

  • John C. Piacentini, PhD

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Purpose
TREATMENT
Sponsor Type
NIH

Study Record Dates

First Submitted

November 2, 1999

First Posted

November 3, 1999

Study Start

December 1, 1998

Study Completion

November 1, 2003

Last Updated

February 12, 2008

Record last verified: 2008-02

Locations