NCT00000334

Brief Summary

The purpose of this study is to compare agonist and antagonist profile associated with buprenorphine vs. methadone during opiate withdrawal.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Dec 2002

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 20, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 21, 1999

Completed
3.2 years until next milestone

Study Start

First participant enrolled

December 1, 2002

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2004

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2005

Completed
Last Updated

January 31, 2017

Status Verified

December 1, 2002

Enrollment Period

1.9 years

First QC Date

September 20, 1999

Last Update Submit

January 30, 2017

Conditions

Opioid-Related Disorders

Outcome Measures

Primary Outcomes (2)

  • Withdrawal severity

  • Opiate agonist symptoms

Interventions

BuprenorphineDRUG

Eligibility Criteria

Age23 Years - 45 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Please contact site for information.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Washington DC VA

Washington D.C., District of Columbia, 20422, United States

Location

MeSH Terms

Conditions

Opioid-Related Disorders

Interventions

Buprenorphine

Condition Hierarchy (Ancestors)

Narcotic-Related DisordersSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

MorphinansOpiate AlkaloidsAlkaloidsHeterocyclic CompoundsHeterocyclic Compounds, Bridged-RingHeterocyclic Compounds, 4 or More RingsHeterocyclic Compounds, Fused-RingPhenanthrenesPolycyclic Aromatic HydrocarbonsPolycyclic Compounds

Study Officials

  • Steven Deutsch, M.D.

    Washington D.C. Veterans Affairs Medical Center

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 2
Purpose
TREATMENT
Sponsor Type
NIH

Study Record Dates

First Submitted

September 20, 1999

First Posted

September 21, 1999

Study Start

December 1, 2002

Primary Completion

November 1, 2004

Study Completion

January 15, 2005

Last Updated

January 31, 2017

Record last verified: 2002-12

Locations

US(1)