NCT00000248

Brief Summary

The purpose of this study is to evaluate the efficacy and safety of pergolide for treatment of cocaine dependence.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 1996

Completed
3.6 years until next milestone

First Submitted

Initial submission to the registry

September 20, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 21, 1999

Completed
Last Updated

May 16, 2018

Status Verified

May 1, 1997

First QC Date

September 20, 1999

Last Update Submit

May 15, 2018

Conditions

Cocaine-Related Disorders

Outcome Measures

Primary Outcomes (6)

  • Side effects

  • Drug use

  • Retention

  • Cocaine withdrawal

  • Compliance

  • Effectiveness of medication for global improvements

Interventions

PergolideDRUG

Eligibility Criteria

Age21 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Please contact site for information.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Medical University of South Carolina

Charleston, South Carolina, 29425 742, United States

Location

Related Publications (1)

  • Malcolm R, Moore JW, Kajdasz DK, Cochrane CE. Pergolide mesylate. Adverse events occurring in the treatment of cocaine dependence. Am J Addict. 1997 Spring;6(2):117-23. doi: 10.3109/10550499709137022.

    PMID: 9134073BACKGROUND

MeSH Terms

Conditions

Cocaine-Related Disorders

Interventions

Pergolide

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

ErgolinesErgot AlkaloidsAlkaloidsHeterocyclic CompoundsHeterocyclic Compounds, 4 or More RingsHeterocyclic Compounds, Fused-Ring

Study Officials

  • Robert Malcolm, M.D.

    Medical University of South Carolina

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 3
Purpose
TREATMENT
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 20, 1999

First Posted

September 21, 1999

Study Start

February 1, 1996

Last Updated

May 16, 2018

Record last verified: 1997-05

Locations

US(1)