NCT00000216

Brief Summary

The purpose of this study is to compare the clinical efficacy of maintenance on low and high doses of buprenorphine with methadone for cocaine abusing opiate addicts.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 20, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 21, 1999

Completed
5.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2005

Completed
Last Updated

June 29, 2020

Status Verified

June 1, 2020

First QC Date

September 20, 1999

Last Update Submit

June 24, 2020

Conditions

Cocaine-Related DisordersOpioid-Related DisordersSubstance-Related Disorders

Keywords

Opioid-Related Disorders

Outcome Measures

Primary Outcomes (5)

  • Depression

  • Withdrawal symptoms

  • Opioid and cocaine use

  • Social and psychological functioning

  • AIDS risk behavior

Interventions

BuprenorphineDRUG

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Please contact site for information.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

APT Residential Services Division

New Haven, Connecticut, 06519, United States

Location

Related Publications (1)

  • Schottenfeld RS, Pakes JR, Oliveto A, Ziedonis D, Kosten TR. Buprenorphine vs methadone maintenance treatment for concurrent opioid dependence and cocaine abuse. Arch Gen Psychiatry. 1997 Aug;54(8):713-20. doi: 10.1001/archpsyc.1997.01830200041006.

    PMID: 9283506BACKGROUND

MeSH Terms

Conditions

Cocaine-Related DisordersOpioid-Related DisordersSubstance-Related Disorders

Interventions

Buprenorphine

Condition Hierarchy (Ancestors)

Chemically-Induced DisordersMental DisordersNarcotic-Related Disorders

Intervention Hierarchy (Ancestors)

MorphinansOpiate AlkaloidsAlkaloidsHeterocyclic CompoundsHeterocyclic Compounds, Bridged-RingHeterocyclic Compounds, 4 or More RingsHeterocyclic Compounds, Fused-RingPhenanthrenesPolycyclic Aromatic HydrocarbonsPolycyclic Compounds

Study Officials

  • Richard Schottenfeld, M.D.

    Yale University

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 3
Purpose
TREATMENT
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 20, 1999

First Posted

September 21, 1999

Study Completion

January 1, 2005

Last Updated

June 29, 2020

Record last verified: 2020-06

Locations

US(1)