Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

9.1%

1 terminated/withdrawn out of 11 trials

Success Rate

75.0%

-11.5% vs industry average

Late-Stage Pipeline

9%

1 trials in Phase 3/4

Results Transparency

0%

0 of 3 completed trials have results

Key Signals

3 recruiting

Enrollment Performance

Analytics

Phase 1
7(63.6%)
Phase 2
3(27.3%)
Phase 3
1(9.1%)
11Total
Phase 1(7)
Phase 2(3)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (11)

Showing 11 of 11 trials
NCT05698524Phase 1Recruiting

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

Role: collaborator

NCT03939182Phase 1Completed

Abexinostat and Ibrutinib in Diffuse Large B-cell Lymphoma and Mantle Cell Lymphoma

Role: collaborator

NCT03592472Phase 3Recruiting

A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)

Role: lead

NCT05275374Phase 1Not Yet Recruiting

XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 Mutation

Role: lead

NCT03934567Phase 2Active Not Recruiting

A Multi-Center Phase 2 Study to Evaluate Efficacy and Safety of Oral Abexinostat as Monotherapy in Patients With Relapsed or Refractory Follicular Lymphoma

Role: lead

NCT04024696Phase 1Active Not Recruiting

A Clinical Study to Evaluate Pharmacokinetics, Safety, and Tolerability of Abexinostat in Chinese Patients

Role: lead

NCT03600441Phase 2Active Not Recruiting

Study of Abexinostat in Patients With Relapsed or Refractory Follicular Lymphoma

Role: lead

NCT03936153Phase 2Recruiting

Study to Evaluate Efficacy and Safety of Oral Abexinostat in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Role: lead

NCT01543763Phase 1Completed

Pazopanib in Combination With PCI-24781 in Patients With Metastatic Solid Tumors

Role: collaborator

NCT03590054Phase 1Completed

Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

Role: collaborator

NCT04498520Phase 1Withdrawn

Abexinostat, Palbociclib, and Fulvestrant for the Treatment of Breast or Gynecologic Cancer

Role: collaborator

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