Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

35.7%

5 terminated/withdrawn out of 14 trials

Success Rate

61.5%

-25.0% vs industry average

Late-Stage Pipeline

21%

3 trials in Phase 3/4

Results Transparency

50%

4 of 8 completed trials have results

Key Signals

1 recruiting4 with results

Enrollment Performance

Analytics

Phase 2
7(50.0%)
Phase 1
4(28.6%)
Phase 3
3(21.4%)
14Total
Phase 2(7)
Phase 1(4)
Phase 3(3)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT06334133Phase 3Recruiting

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes

Role: lead

NCT03335371Phase 1Completed

Evaluation of TTP399 in Patients With Type 1 Diabetes

Role: lead

NCT03980730Phase 2Terminated

Study of Azeliragon in Patients With Mild Alzheimer's Disease and Impaired Glucose Tolerance

Role: lead

NCT02916056Phase 3Terminated

2-Year Extension Study of Azeliragon in Subjects With Alzheimer's Disease (STEADFAST Extension)

Role: lead

NCT02080364Phase 3Terminated

Evaluation of the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease

Role: lead

NCT02405260Phase 2Completed

Add Glucokinase Activator to Target A1c

Role: lead

NCT02653599Phase 2Completed

A Study to Evaluate Safety and Efficacy of TTP273 for 12 Weeks in Subjects With Type 2 Diabetes

Role: lead

NCT01665352Phase 2Completed

A Study to Evaluate Safety and Efficacy of TTP054 for 12 Weeks in Subjects With Type 2 Diabetes

Role: lead

NCT01548430Phase 1Completed

A Safety Study of TTP4000 in Subjects With Alzheimer's Disease

Role: lead

NCT01474083Phase 1Completed

A 6 Week Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of GK1-399 in Type 2 Diabetes

Role: lead

NCT00939172Phase 1Withdrawn

TTP607 in Refractory Solid Malignancies

Role: collaborator

NCT00779519Phase 2Completed

Safety Study of the Inhibition of Agouti-related Protein (AgRP) for the Management of Obesity and Weight Loss

Role: lead

NCT00909298Phase 2Terminated

Left Ventricular Assist Device (LVAD) Specialized Centers of Clinically Orientated Research (SCCOR) Coagulation - Acute Intrinsic Pathway Antagonist (IPA)

Role: lead

NCT00119457Phase 2Completed

Factor IX Inhibition in Thrombosis Prevention (The FIXIT Trial)

Role: lead

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