Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 90/100

Failure Rate

41.7%

5 terminated/withdrawn out of 12 trials

Success Rate

50.0%

-36.5% vs industry average

Late-Stage Pipeline

17%

2 trials in Phase 3/4

Results Transparency

40%

2 of 5 completed trials have results

Key Signals

2 with results4 withdrawn

Enrollment Performance

Analytics

Phase 1
7(70.0%)
Phase 4
2(20.0%)
Phase 2
1(10.0%)
10Total
Phase 1(7)
Phase 4(2)
Phase 2(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT03594461Phase 1Unknown

Intense Treatment Regimen With Intravitreal Aflibercept Injection

Role: lead

NCT01495221Phase 4Completed

To Evaluate The Role of Intravitreal Aflibercept Injection (2.0 mg) in the Management of Previously Treated Patients With Exudative AMD

Role: lead

NCT01495208Phase 4Withdrawn

Open Label to Study to Evaluate Effect of Alfilbercept on Patients With (FVPED) Fibrovascular Pigment Epithelial Detachment

Role: lead

NCT01115556Phase 1Completed

A Pilot Study to Evaluate the Role of High-dose Ranibizumab (2.0mg) in the Management of AMD in Patients With Persistent/Recurrent Macular Fluid Less Than 30 Days Following Treatment With Intravitreal Anti-VEGF Therapy (the LAST Study)

Role: lead

NCT00457678Phase 2Withdrawn

Second Line Therapy to Treat Age-related Macular Degeneration (AMD) for Patients Not Responding Well to Lucentis Therapy by Itself

Role: lead

NCT01714115Unknown

Use of Eylea for the Treatment of an Optic Nerve Hemangioma

Role: lead

NCT00403039Phase 1Completed

Intravitreal Ranibizumab Treatment of Central Retinal Vein Occlusion With Macular Edema

Role: lead

NCT00403156Phase 1Withdrawn

Imatinib Mesylate Combined With Intravitreal Ranibizumab in the Treatment of Choroidal Neovascularization Secondary to Age-Related Macular Degeneration

Role: lead

NCT01880788Completed

Genetic Analysis of Chronic Central Serous Chorioretinopathy Masquerading as Neovascular AMD

Role: collaborator

NCT00726466Phase 1Withdrawn

Study of Efalizumab Combined With Intravitreal Ranibizumab in the Treatment of Age-Related Macular Degeneration

Role: lead

NCT00403325Phase 1Completed

Intravitreal Ranibizumab Treatment of Central Serous Chorioretinopathy

Role: lead

NCT00403442Phase 1Terminated

Bevacizumab in Combination With Verteporfin Reduced and Standard Fluence in the Treatment of Hemorrhaged Lesions in Neovascular AMD

Role: lead

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