Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

8.3%

1 terminated/withdrawn out of 12 trials

Success Rate

90.9%

+4.4% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

30%

3 of 10 completed trials have results

Key Signals

3 with results

Enrollment Performance

Analytics

Phase 1
10(83.3%)
Phase 2
2(16.7%)
12Total
Phase 1(10)
Phase 2(2)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT03408587Phase 1Completed

CAVATAK® and Ipilimumab in Uveal Melanoma Metastatic to the Liver (VLA-024 CLEVER)

Role: lead

NCT02043665Phase 1Completed

CVA21 and Pembrolizumab in NSCLC & Bladder Cancer (VLA-009 STORM/ KEYNOTE-200)

Role: lead

NCT02307149Phase 1Completed

Intratumoral CAVATAK (CVA21) and Ipilimumab in Patients With Advanced Melanoma (VLA-013 MITCI)

Role: lead

NCT02565992Phase 1Completed

Intratumoral CAVATAK (CVA21) and Pembrolizumab in Patients With Advanced Melanoma (VLA-011 CAPRA)

Role: lead

NCT02316171Phase 1Completed

CAVATAK (CVA21) in Non-muscle Invasive Bladder Cancer (VLA-012 CANON)

Role: lead

NCT02824965Phase 1Unknown

Pembrolizumab + CVA21 in Advanced NSCLC

Role: collaborator

NCT00832559Phase 1Terminated

A Study of the Intratumoural Administration of CAVATAK to Head and Neck Cancer Patients (VLA-X06)

Role: lead

NCT01636882Phase 2Completed

CAVATAK in Patients With Stage IIIc or IV Malignant Melanoma to Extend Dosing to 48 Weeks (VLA-008 CALM Ext)

Role: lead

NCT01227551Phase 2Completed

A Study of Intratumoral CAVATAK™ in Patients With Stage IIIc and Stage IV Malignant Melanoma (VLA-007 CALM )

Role: lead

NCT00636558Phase 1Completed

Coxsackie Virus A21 Administered Intravenously (IV) for Solid Tumour Cancers (PSX-X04)

Role: lead

NCT00438009Phase 1Completed

A Safety Study of Two Intratumoural Doses of Coxsackievirus Type A21 in Melanoma Patients (PSX-X03)

Role: lead

NCT00235482Phase 1Completed

Intratumoural Administration of Coxsackievirus A21 for the Control of Malignant Melanoma (PXS-X02)

Role: lead

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