Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

14.3%

5 terminated/withdrawn out of 35 trials

Success Rate

78.3%

-8.2% vs industry average

Late-Stage Pipeline

14%

5 trials in Phase 3/4

Results Transparency

89%

16 of 18 completed trials have results

Key Signals

5 recruiting16 with results

Enrollment Performance

Analytics

Phase 2
14(42.4%)
Phase 1
14(42.4%)
Phase 3
5(15.2%)
33Total
Phase 2(14)
Phase 1(14)
Phase 3(5)

Activity Timeline

Global Presence

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Clinical Trials (35)

Showing 20 of 35 trials
NCT07128550Phase 3Recruiting

A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide

Role: lead

NCT04856085Phase 2Completed

Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection

Role: lead

NCT05997615Phase 1Recruiting

Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer

Role: lead

NCT04412863Phase 2Completed

Study of VIR-2218 With or Without Pegylated Interferon Alpha-2a for Treatment of Chronic Hepatitis B Virus Infection

Role: lead

NCT06960395Phase 1Recruiting

Safety and Preliminary Efficacy of VIR-5525 and VIR-5525 + Pembrolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Role: lead

NCT06903338Phase 3Active Not Recruiting

A Study to Evaluate Tobevibart + Elebsiran in Chronic HDV Infection

Role: lead

NCT05612581Phase 1Completed

A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection

Role: lead

NCT07142811Phase 2Active Not Recruiting

A Study to Evaluate Tobevibart+Elebsiran Versus Bulevirtide in Chronic HDV Infection

Role: lead

NCT05461170Phase 2Active Not Recruiting

SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.

Role: lead

NCT05356741Phase 1Recruiting

To Access the Safety and Effects of Intravenous Administration of VIR-5818 Alone and in Combination With Pembrolizumab in Adult Participants With Locally Advanced or Metastatic HER2-Expressing Cancers

Role: lead

NCT05970289Phase 2Active Not Recruiting

Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV Patients

Role: collaborator

NCT04891770Phase 2Completed

Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB)

Role: collaborator

NCT05844228Phase 1Completed

A Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics and Safety of VIR-2218

Role: lead

NCT05484206Phase 1Recruiting

Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434

Role: lead

NCT06070051Phase 1Active Not Recruiting

Dose-Escalation Prime/Boost Therapeutic Vaccination Study Of 2 Chimp Adenoviral Vectors in Adults With Chronic HBV On Nucleos(t)Ide Therapy

Role: collaborator

NCT05135650Phase 1Terminated

Pharmacokinetics of Sotrovimab as Pre-exposure Prophylaxis for COVID-19 in Hematopoietic Stem Cell Transplant Recipients, COVIDMAB Study

Role: collaborator

NCT06491563Phase 2Active Not Recruiting

Study to Investigate the Efficacy and Safety of Regimens Containing BRII-179, BRII-835, and PEG-IFNα Treating Chronic Hepatitis B Virus (HBV) Infection (ENRICH)

Role: collaborator

NCT04423393Phase 1Completed

Study of VIR-3434 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus Infection

Role: lead

NCT05567783Phase 2Terminated

A Phase 2 Study to Evaluate the Efficacy and Safety of VIR-2482 for the Prevention of Illness Due to Influenza A

Role: lead

NCT05280717Phase 1Terminated

Relative Bioavailability, Safety, and Tolerability of Single-dose Sotrovimab Injection in Adults (COSMIC)

Role: lead