Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

0.0%

0 terminated/withdrawn out of 17 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

18%

3 trials in Phase 3/4

Results Transparency

73%

11 of 15 completed trials have results

Key Signals

2 recruiting11 with results

Enrollment Performance

Analytics

Phase 2
13(76.5%)
Phase 3
3(17.6%)
Phase 1
1(5.9%)
17Total
Phase 2(13)
Phase 3(3)
Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (17)

Showing 17 of 17 trials
NCT07016412Phase 2Recruiting

A Phase IIb Ensifentrine-glycopyrrolate Fixed-dose Combination Dose Ranging Study in Subjects With COPD

Role: lead

NCT05270525Phase 2Recruiting

Effect of Ensifentrine on Sputum Markers of Inflammation in COPD

Role: lead

NCT06545500Phase 2Completed

A Phase IIb Study of Glycopyrrolate Inhalation Solution Over 1 Week in Subjects With COPD

Role: lead

NCT07132983Phase 2Completed

A Phase II Study to Assess the Pharmacokinetics, Pharmacodynamics, and Safety of Single Inhaled Doses of Ensifentrine-glycopyrrolate Fixed Dose Combination, Ensifentrine, and Glycopyrrolate in Subjects With Chronic Obstructive Pulmonary Disease

Role: lead

NCT06460493Phase 3Completed

Effect of Ensifentrine Treatment on CAT Score

Role: lead

NCT02919995Phase 2Completed

A Study of RPL554 in Patients With Cystic Fibrosis

Role: lead

NCT04535986Phase 3Completed

A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

Role: lead

NCT04542057Phase 3Completed

A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

Role: lead

NCT04027439Phase 2Completed

Study Evaluating 5 Doses of RPL554 and Placebo in COPD Patients Via a Dry Powder Inhaler

Role: lead

NCT04091360Phase 2Completed

A Study of RPL554 Drug Administered by Metered Dose Inhaler to Treat Chronic Obstructive Pulmonary Disease

Role: lead

NCT03937479Phase 2Completed

Study Investigating the Effect of 4 Doses of RPL554 Given in Addition to Tiotropium to Patients With COPD

Role: lead

NCT03673670Phase 2Completed

Bronchodilator Effect of RPL554 Administered in Addition to Tiotropium/Olodaterol in Patients With COPD

Role: lead

NCT03443414Phase 2Completed

Dose Ranging Study of RPL554 in Chronic Obstructive Pulmonary Disease (COPD) Patients

Role: lead

NCT03028142Phase 2Completed

The Effects of RPL554 in Addition to Tiotropium in COPD Patients

Role: lead

NCT02427165Phase 2Completed

Comparison of RPL554 With Placebo and Salbutamol in Asthmatic Patients

Role: lead

NCT02542254Phase 2Completed

The Effects of RPL554 on Top of Standard COPD Reliever Medications

Role: lead

NCT02307162Phase 1Completed

SAD/MAD Study of a New Formulation of Nebulised RPL554 in Healthy Subjects and COPD Subjects

Role: lead

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