Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

8.3%

2 terminated/withdrawn out of 24 trials

Success Rate

90.9%

+4.4% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

35%

7 of 20 completed trials have results

Key Signals

7 with results

Enrollment Performance

Analytics

Phase 1
18(75.0%)
Phase 2
6(25.0%)
24Total
Phase 1(18)
Phase 2(6)

Activity Timeline

Global Presence

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Clinical Trials (24)

Showing 20 of 24 trials
NCT07254728Phase 1Completed

A Study to Evaluate Vaxart's Oral Bivalent GI.1/GII.4 Norovirus Vaccine in Healthy Lactating Females and Their Nursing Infants

Role: lead

NCT05212168Phase 1Completed

Norovirus Challenge Study

Role: lead

NCT06672055Phase 2Active Not Recruiting

A Study to Evaluate VXA-CoV2-3.3 COVID-19 Vaccine Against Currently Approved/Authorized mRNA COVID-19 Injectable Booster Vaccine in Adults Previously Immunized Against COVID-19 Infection

Role: lead

NCT06944717Phase 1Active Not Recruiting

A Trial of a Norovirus G1.1 and G2.4 Vaccine Administered Orally to Healthy Participants Aged ≥ 18 Years and ≤ 80 Years Old

Role: lead

NCT05626803Phase 2Completed

A Study to Determine the Safety and Immunogenicity of Bivalent GI.1 and GII.4 Vaccines in Healthy Volunteers

Role: lead

NCT05067933Phase 2Terminated

A Ph 2 Trial With an Oral Tableted COVID-19 Vaccine

Role: lead

NCT05213728Phase 1Completed

A Phase 1, Open-label, Safety and Immunogenicity Study of an Oral Multi-dose Administration Regimen With an Adenoviral-vector Based Tablet Norovirus Vaccine (VXA-G1.1-NN) Administered to Healthy Adult Volunteers

Role: lead

NCT04563702Phase 1Completed

Safety and Immunogenicity Trial of an Oral SARS-CoV-2 Vaccine (VXA-CoV2-1) for Prevention of COVID-19 in Healthy Adults and Boost (VXA-CoV2-1.1-S) at 1 Year Post Initial Vaccination in Subset of Subjects

Role: lead

NCT04875676Phase 1Completed

Immunogenicity & Safety Study of Adenovirus Type 5 (AD5) Based Oral Norovirus Vaccines

Role: lead

NCT04854746Phase 1Completed

Ph 1b: Safety & Immunogenicity of Ad5 Based Oral Norovirus Vaccine

Role: lead

NCT02918006Phase 2Completed

A Phase 2 Influenza A Challenge Study Following Oral Administration of an H1N1 HA Ad-Vector Seasonal Flu Vaccine

Role: lead

NCT03897309Phase 1Completed

Safety & Immunogenicity Study of Ad5 Based Oral Norovirus Vaccines

Role: lead

NCT03721549Phase 1Completed

Evaluation of Infectivity and Illness of Norwalk GI.1 Virus Lot 001-09NV in the Human Challenge Model

Role: collaborator

NCT02830932Phase 1Completed

Dose-Ranging Trial of Safety & Immunogenicity of an Oral Adenoviral-Vector Based RSV Vaccine (VXA-RSV-f)

Role: lead

NCT02724254Phase 2Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Topical Applications of AP611074 5% Gel for up to 16 Weeks in Condyloma Patients

Role: lead

NCT02547792Phase 1Completed

Assessment of an Oral Influenza B Vaccine Tablet (VXA-BYW.10) Following Single Dose Administration in Healthy Adults

Role: lead

NCT02868073Phase 1Completed

Phase 1 Placebo-controlled, Randomized Trial of an Adenoviral-vector Based Norovirus Vaccine

Role: lead

NCT03121339Phase 1Completed

Pharmacodynamic Open-Label Trial With VXA-A1.1 Oral H1 Vaccine in Healthy Adults

Role: lead

NCT03125473Phase 1Completed

Dose-Optimization Trial of VXA-G1.1-NN in Healthy Volunteers

Role: lead

NCT03024177Phase 2Withdrawn

A Study of Vapendavir Treatment of Hematopoietic Stem Cell Transplant Subjects With Symptomatic Rhinovirus Infection

Role: lead