Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 15/100

Failure Rate

8.0%

4 terminated/withdrawn out of 50 trials

Success Rate

90.7%

+4.2% vs industry average

Late-Stage Pipeline

48%

24 trials in Phase 3/4

Results Transparency

54%

21 of 39 completed trials have results

Key Signals

21 with results4 withdrawn

Enrollment Performance

Analytics

Phase 3
22(50.0%)
Phase 2
11(25.0%)
Phase 1
9(20.5%)
Phase 4
2(4.5%)
44Total
Phase 3(22)
Phase 2(11)
Phase 1(9)
Phase 4(2)

Activity Timeline

Global Presence

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Clinical Trials (50)

Showing 20 of 50 trials
NCT06334393Phase 1Completed

Phase 1 Trial to Assess the Safety and Immunogenicity of an Inactivated, Adjuvanted Whole Zika Virus Vaccine Candidate (VLA1601) in Healthy Adults

Role: lead

NCT07414524Not Yet Recruiting

VLA1553-403 Pregnancy Surveillance Study

Role: lead

NCT07254702Enrolling By Invitation

Prospective Safety Cohort Study After VLA1553 Vaccination in Municipalities Selected for Participation in the VLA1553 Pilot Vaccination Strategy in Brazil

Role: lead

NCT07347002Enrolling By Invitation

Observational Study to Assess the Effectiveness of VLA1553 Vaccine in Preventing Chikungunya During a Pilot Vaccination Strategy in Brazil

Role: lead

NCT07163845Active Not Recruiting

Assessment of Chikungunya Virus Seroprevalence Before VLA1553 Vaccination in the Municipalities Selected for Participation in the VLA1553 Pilot Vaccination Strategy in Brazil

Role: lead

NCT07133178Phase 3Withdrawn

A Trial to Evaluate the Safety and Immunogenicity of VLA1553 in Healthy Children

Role: lead

NCT04838444Phase 3Active Not Recruiting

Antibody Persistence And Long Term Safety Of A Chikungunya Virus Vaccine (VLA1553)

Role: lead

NCT04801420Phase 2Completed

Phase 2 Study Of VLA15, A Vaccine Candidate Against Lyme Borreliosis, In A Healthy Pediatric And Adult Study Population

Role: collaborator

NCT05477524Phase 3Active Not Recruiting

An Efficacy, Safety, Tolerability, Immunogenicity, and Lot-Consistency Clinical Trial of a 6-Valent OspA-Based Lyme Disease Vaccine (VLA15)

Role: collaborator

NCT06106581Phase 2Completed

A Phase 2 Clinical Trial of VLA1553 in Healthy Children Aged 1 to 11 Years

Role: lead

NCT06028841Phase 3Withdrawn

A Clinical Phase 3 Trial of VLA1553 in Adult Participants with Human Immunodeficiency Virus (HIV)

Role: lead

NCT04650399Phase 3Completed

A Multicenter Study to Evaluate Safety and Immunogenicity of a Live-attenuated Chikungunya Vaccine in Adolescents

Role: collaborator

NCT00605085Phase 3Completed

Safety and Tolerability of the Japanese Encephalitis Vaccine IC51

Role: lead

NCT00594958Phase 3Completed

Comparison of Three Batches of the Japanese Encephalitis Vaccine IC51

Role: lead

NCT00604708Phase 3Completed

Immunogenicity Study of the Japanese Encephalitis Vaccine IC51

Role: lead

NCT04786444Phase 3Completed

Study to Demonstrate Consistency of Three Lots of a Live-attenuated Chikungunya Virus Vaccine Candidate in Healthy Adults

Role: lead

NCT04956224Phase 3Completed

Safety and Immunogenicity of VLA2001 Adults Aged ≥56 Years

Role: lead

NCT04546724Phase 3Completed

Pivotal Study to Evaluate Safety and Immunogenicity of a Live-Attenuated Chikungunya Virus Vaccine Candidate in Adults

Role: lead

NCT05364242Phase 2Completed

VLA2001 Booster in Adult Participants After Priming With mRNA COVID-19 Vaccine and/or Natural SARS-CoV-2 Infection

Role: lead

NCT03970733Phase 2Completed

Alternative Schedule Study For VLA15, a Vaccine Candidate Against Lyme Borreliosis

Role: collaborator