Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

3.0%

2 terminated/withdrawn out of 67 trials

Success Rate

96.0%

+9.5% vs industry average

Late-Stage Pipeline

12%

8 trials in Phase 3/4

Results Transparency

10%

5 of 48 completed trials have results

Key Signals

8 recruiting5 with results

Enrollment Performance

Analytics

N/A
35(71.4%)
Phase 2
5(10.2%)
Phase 3
5(10.2%)
Phase 4
3(6.1%)
Phase 1
1(2.0%)
49Total
N/A(35)
Phase 2(5)
Phase 3(5)
Phase 4(3)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (67)

Showing 20 of 67 trials
NCT01509508Not ApplicableCompleted

Impact of Immediate Versus South African Recommendations Guided ART Initiation on HIV Incidence

Role: collaborator

NCT05373758Not ApplicableRecruiting

A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa

Role: collaborator

NCT06035445Not ApplicableActive Not Recruiting

Support for Adolescents Living With HIV in South Africa

Role: collaborator

NCT06248190Not ApplicableCompleted

ENHANCE-EvideNce Led Co-created HeAlth Systems interventioNs for MLTCs CarE

Role: lead

NCT06429475Phase 3Recruiting

Anti-Inflammatory Reliever South Africa

Role: lead

NCT07339462Not ApplicableRecruiting

Feasibility and Acceptability of an Intervention to Support People With Severe Mental Illness in South Africa

Role: lead

NCT06285110Completed

HIV-1 Subtype-specific Drug Resistance in Patients Failing Dolutegravir (DTG) Based Regimen

Role: collaborator

NCT05681871Phase 4Completed

South African Paediatric Surgical Outcomes Study 2

Role: collaborator

NCT04426448Not ApplicableRecruiting

Assessment of a Brief Post Traumatic Stress Disorder Intervention for Use in Botswana

Role: collaborator

NCT00664313Phase 1Completed

TBTC Study 30: Safety and Tolerability of Low Dose Linezolid in MDR TB

Role: collaborator

NCT06933303Not ApplicableRecruiting

Distraction as Treatment for Pain in Children in Resource-scarce Settings

Role: collaborator

NCT05061407Completed

An African, Multi-centre Evaluation of Patient Care and Clinical Outcomes for Paediatric Patients Undergoing Surgery

Role: lead

NCT04975178Phase 3Recruiting

Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africa

Role: collaborator

NCT06431217Completed

Group B Strep Correlates of Protection Study

Role: collaborator

NCT06516549Not ApplicableRecruiting

Evaluation of Skipping Rope and Informational Pamphlet Among Adolescents in South Africa

Role: lead

NCT05982847Recruiting

National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa

Role: collaborator

NCT05022212Phase 2Completed

Phase 2 Trial of LACTIN-V in Women at High Risk of HIV Acquisition

Role: collaborator

NCT04583904Completed

Prospective Evaluation of Novel Diagnostics for Tuberculosis in KwaZulu-Natal, South Africa

Role: collaborator

NCT04794660Phase 3Active Not Recruiting

The Study for the "Cervical Cancer Screening and Treatment Algorithms Study Using HPV Testing in Africa"

Role: collaborator

NCT04746547Phase 4Unknown

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB

Role: lead