Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

12.5%

2 terminated/withdrawn out of 16 trials

Success Rate

87.5%

+1.0% vs industry average

Late-Stage Pipeline

19%

3 trials in Phase 3/4

Results Transparency

43%

6 of 14 completed trials have results

Key Signals

6 with results

Enrollment Performance

Analytics

Phase 1
9(56.3%)
Phase 2
4(25.0%)
Phase 3
3(18.8%)
16Total
Phase 1(9)
Phase 2(4)
Phase 3(3)

Activity Timeline

Global Presence

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Clinical Trials (16)

Showing 16 of 16 trials
NCT04201080Phase 1Terminated

A Trial to Evaluate the Efficacy, Safety and Tolerability of Subcutaneous TRV250

Role: lead

NCT02820324Phase 3Completed

Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Abdominoplasty

Role: lead

NCT02815709Phase 3Completed

Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Bunionectomy

Role: lead

NCT02656875Phase 3Completed

A Open-label Study to Evaluate the Safety of TRV130 in Patients With Acute Pain

Role: lead

NCT02100748Phase 2Completed

A Study of TRV130 for the Treatment of Pain After Bunionectomy

Role: lead

NCT02335294Phase 2Completed

A Study of TRV130 for the Treatment of Pain After Abdominoplasty

Role: lead

NCT02520297Phase 2Terminated

A Pilot Study of TRV130 for the Treatment of Fracture Pain

Role: lead

NCT01966601Phase 2Completed

A Study to Explore the Efficacy of TRV027 in Patients Hospitalized for Acute Decompensated Heart Failure

Role: lead

NCT01187836Phase 1Completed

Study to Evaluate the Effects of TRV120027 in Patients With Heart Failure

Role: lead

NCT02344303Phase 1Completed

Study of the Effects of TRV130, at Therapeutic and Supra Therapeutic Doses, on QTc Intervals

Role: lead

NCT02411500Phase 1Completed

A Pharmacokinetic, Safety and Tolerability Study in Healthy Adult Males

Role: lead

NCT02169934Phase 1Completed

A Study to Investigate the Metabolism and Excretion of [14C]-TRV130 in Healthy Male Subjects

Role: lead

NCT02211625Phase 1Completed

A Safety, Tolerability, PD and PK Study in Healthy Adults

Role: lead

NCT02083315Phase 1Completed

Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Subjects

Role: lead

NCT01444872Phase 1Completed

Study to Evaluate TRV120027 on Renal Pharmacodynamics in Patients With Heart Failure and Renal Dysfunction

Role: lead

NCT01514578Phase 1Completed

Single Ascending Dose Study of Intravenous TRV130A in Healthy Adult Males

Role: lead

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