Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

0.0%

0 terminated/withdrawn out of 18 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

11%

2 trials in Phase 3/4

Results Transparency

0%

0 of 9 completed trials have results

Key Signals

4 recruiting

Enrollment Performance

Analytics

Phase 1
11(64.7%)
Phase 2
4(23.5%)
Phase 3
2(11.8%)
17Total
Phase 1(11)
Phase 2(4)
Phase 3(2)

Activity Timeline

Global Presence

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Clinical Trials (18)

Showing 18 of 18 trials
NCT07498478Phase 2Recruiting

Efficacy and Safety of Tinengotinib Tablets Combined With Fulvestrant Injection in Patients With HR Positive and HER-2 Negative Recurrent or Metastatic Breast Cancer Who Have Failed Prior Treatment

Role: lead

NCT07052253Phase 2Recruiting

A Phase II Clinical Study of AK104/AK112 in Combination With TT-00420 Tablet for Advanced HCC.

Role: collaborator

NCT07328919Phase 3Not Yet Recruiting

Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or Mutations

Role: lead

NCT06057571Phase 2Active Not Recruiting

Study of TT-00420 (Tinengotinib) in Subjects With Cholangiocarcinoma Who Failed or Relapsed to Chemotherapy and FGFR Inhibitor

Role: lead

NCT03654547Phase 1Completed

Safety of TT-00420 (Tinengotinib) Monotherapy in Patients With Advanced Solid Tumors and Triple Negative Breast Cancer

Role: lead

NCT05253053Phase 1Completed

To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

Role: lead

NCT04919642Phase 2Completed

Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma

Role: lead

NCT05948475Phase 3Recruiting

Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma

Role: lead

NCT04742959Phase 1Completed

Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

Role: lead

NCT06370013Unknown

Rollover Study to Provide Continued Access to TT-00420 (Tinengotinib) for Subjects With Advanced Solid Tumors

Role: lead

NCT04705922Phase 1Completed

Relative Bioavailability Study and Food Effect Study of TT-00420 (Tinengotinib) Capsule and Tablet Formulations in Healthy Volunteers

Role: lead

NCT04830501Phase 1Completed

Study of the of the Safety and Tolerability of TT-00434 in Patients With Advanced Solid Tumors

Role: lead

NCT05683717Phase 1Recruiting

A Phase 1 Study to Evaluate the Safety and Tolerability of TT-01488 in Patients With B-Cell Malignancies

Role: lead

NCT05043792Phase 1Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Dose of TT-00920 in Healthy Subjects

Role: lead

NCT05355129Phase 1Completed

A Phase 1 Study of TT-00920 in Healthy Subjects

Role: lead

NCT04364789Phase 1Completed

Phase I, First-In-Human Study of TT-00920 in Healthy Subjects

Role: lead

NCT05673538Phase 1Unknown

TT-00973-MS Tablets in Patients With Advanced Solid Tumors

Role: lead

NCT05275504Phase 1Unknown

Study to Evaluate the Safety and Tolerability of TT-01488 in Patients With B-Cell Malignancies

Role: lead

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