Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 50/100

Failure Rate

12.1%

4 terminated/withdrawn out of 33 trials

Success Rate

71.4%

-15.1% vs industry average

Late-Stage Pipeline

6%

2 trials in Phase 3/4

Results Transparency

50%

5 of 10 completed trials have results

Key Signals

4 recruiting5 with results

Enrollment Performance

Analytics

Phase 2
18(54.5%)
Phase 1
13(39.4%)
Phase 3
2(6.1%)
33Total
Phase 2(18)
Phase 1(13)
Phase 3(2)

Activity Timeline

Global Presence

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Clinical Trials (33)

Showing 20 of 33 trials
NCT04061421Phase 1Recruiting

Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes Overlap Syndromes (ABNL-MARRO)

Role: collaborator

NCT05732103Phase 1Recruiting

A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

Role: collaborator

NCT05077709Phase 2Completed

IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC

Role: collaborator

NCT07033598Phase 2Recruiting

Pacritinib vs. Hydroxyurea in Advanced Proliferative Chronic Myelomonocytic Leukemia

Role: lead

NCT04203641Phase 1Terminated

L-DOS47 Plus Doxorubicin in Advanced Pancreatic Cancer

Role: collaborator

NCT03008187Phase 1Completed

MEN1703 (SEL24) in Participants With Acute Myeloid Leukemia

Role: collaborator

NCT03402841Phase 3Completed

Multicentre Study of Olaparib Maintenance Monotherapy in Platinum Sensitive Relapsed Non gBRCAm Ovarian Cancer Patients

Role: collaborator

NCT02309892Phase 1Terminated

A Dose Escalation Study of L-DOS47 in Recurrent or Metastatic Non-Squamous NSCLC

Role: collaborator

NCT05280314Phase 2Recruiting

Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors

Role: collaborator

NCT02529930Phase 1Completed

An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3)

Role: collaborator

NCT02879669Phase 1Unknown

A Randomised Phase II Open-label Study With a Phase Ib Safety lead-in Cohort of ONCOS-102, an Immune-priming GM-CSF Coding Oncolytic Adenovirus, and Pemetrexed/Cisplatin in Patients With Unresectable Malignant Pleural Mesothelioma

Role: collaborator

NCT01986426Phase 1Completed

LTX-315 in Patients With Transdermally Accessible Tumours as Monotherapy or Combination With Ipilimumab or Pembrolizumab

Role: collaborator

NCT02272855Phase 2Completed

A Study of Combination Treatment With HF10 and Ipilimumab in Patients With Unresectable or Metastatic Melanoma

Role: collaborator

NCT02222363Phase 1Terminated

Study of Safety and Tolerability of VLX600, an Iron Chelator, in Patients With Refractory Advanced Solid Tumors

Role: collaborator

NCT02372240Phase 1Terminated

A Study of VLX1570 and Dexamethasone in Myeloma Patients

Role: collaborator

NCT01035502Phase 2Completed

A Study of Elacytarabine (CP-4055) Plus Idarubicin as Second Course Remission-Induction Therapy in Patients With Acute Myeloid Leukaemia

Role: collaborator

NCT01258816Phase 1Completed

The Pharmacokinetics and Cardiac Properties of Elacytarabine (CP-4055)

Role: collaborator

NCT01308762Phase 1Completed

A Clinical Study, to Evaluate the Safety and Tolerability of Intradermal IMM-101 in Adult Melanoma Cancer Patients

Role: collaborator

NCT00111904Phase 2Completed

Paclitaxel in Treating Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer

Role: lead

NCT00003160Phase 2Unknown

Weekly Infusions of Paclitaxel in Treating Women With Stage III or Stage IV Ovarian Cancer Refractory to Paclitaxel and Platinum

Role: lead