Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 100/100

Failure Rate

33.3%

4 terminated/withdrawn out of 12 trials

Success Rate

60.0%

-26.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

33%

2 of 6 completed trials have results

Key Signals

2 with results

Enrollment Performance

Analytics

Phase 1
9(75.0%)
Phase 2
3(25.0%)
12Total
Phase 1(9)
Phase 2(3)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT02756130Phase 1Withdrawn

Birinapant and Carboplatin in Treating Patients and Targeting Recurrent High Grade Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (HGSOC)

Role: collaborator

NCT01573780Phase 1Terminated

Gemcitabine Hydrochloride and Smac Mimetic TL32711 in Treating Patients With Advanced Solid Tumors

Role: collaborator

NCT02636244Phase 2Unknown

Safety and Efficacy Study of SHAPE Gel in Alopecia Areata

Role: lead

NCT02213861Phase 2Unknown

Efficacy, Safety and Tolerability Study of SHAPE in IA, IB or IIA Cutaneous T-cell Lymphoma

Role: lead

NCT02147873Phase 2Terminated

Study of Azacitidine With or Without Birinapant in Subjects With MDS or CMMoL

Role: lead

NCT01188499Phase 1Completed

Dose Escalation, Combination Chemotherapy Safety Study of Birinapant (TL32711), in Subjects With Advanced or Metastatic Solid Tumors

Role: lead

NCT01828346Phase 1Completed

Birinapant With 5-azacitidine in MDS Subjects Who Are Naïve, Have Relapsed or Are Refractory to 5-azacitidine Therapy

Role: lead

NCT01433731Phase 1Completed

Safety, Pharmacodynamics (PD), Pharmacokinetics (PK) Study of SHP141 in 1A, 1B, or 2A Cutaneous T-Cell Lymphoma (CTCL)

Role: lead

NCT00993239Phase 1Completed

Dose Escalation Safety Study of TL32711 in Adults With Refractory Solid Tumors or Lymphoma

Role: lead

NCT02288208Phase 1Terminated

Phase I Safety and Tolerability Study of Birinapant in Chronic Hepatitis B

Role: lead

NCT01940172Phase 1Completed

Study of Birinapant in Combination With Conatumumab in Subjects With Relapsed Ovarian Cancer

Role: lead

NCT01646567Phase 1Completed

SHP-141C in Plaque Type Psoriasis

Role: lead

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