Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

23.8%

5 terminated/withdrawn out of 21 trials

Success Rate

76.2%

-10.3% vs industry average

Late-Stage Pipeline

19%

4 trials in Phase 3/4

Results Transparency

0%

0 of 16 completed trials have results

Key Signals

Enrollment Performance

Analytics

Phase 2
9(42.9%)
Phase 1
8(38.1%)
Phase 3
4(19.0%)
21Total
Phase 2(9)
Phase 1(8)
Phase 3(4)

Activity Timeline

Global Presence

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Clinical Trials (21)

Showing 20 of 21 trials
NCT00701870Phase 2Terminated

Study of Telintra for Treatment of Chemotherapy Induced Neutropenia in Patients With Non-Small Cell Lung Cancer

Role: lead

NCT00350948Phase 3Terminated

Phase 3 Randomized Study of Telcyta + Doxorubicin Versus Doxorubicin in Platinum Refractory or Resistant Ovarian Cancer

Role: lead

NCT01422486Phase 2Terminated

Phase 2 Study of Telintra® in Deletion 5q Myelodysplastic Syndrome

Role: lead

NCT00909584Phase 2Terminated

Study of Ezatiostat (Telintra Tablets) for Treatment of Severe Chronic Neutropenia

Role: lead

NCT01459159Phase 2Terminated

Study of (Telintra®) in Non-Del(5q) Myelodysplastic Syndrome

Role: lead

NCT01062152Phase 1Completed

Dose-Ranging Study of Telintra® Tablets + Revlimid® in Patients With Non-Deletion (5q) Low to Intermediate-1 Risk Myelodysplastic Syndrome (MDS)

Role: lead

NCT01148108Phase 2Completed

Study of Canfosfamide in Refractory or Relapsed Mantle Cell, Diffuse Large B Cell Lymphoma and Multiple Myeloma

Role: lead

NCT00088556Phase 1Completed

Carboplatin, Paclitaxel and TLK286 (Telcyta) as First-Line Therapy in Advanced Non-Small Cell Lung Cancer

Role: lead

NCT00102973Phase 3Completed

TLK286 (Telcyta) in Combination With Carboplatin (Paraplatin) Versus Doxil in Platinum Refractory or Resistant Ovarian Cancer

Role: lead

NCT00280631Phase 1Completed

Study of TLK199 Tablets in Myelodysplastic Syndrome (MDS)

Role: lead

NCT00700206Phase 2Completed

Phase 2 Study Comparing Two Dose Schedules of Telintra™ in Myelodysplastic Syndrome (MDS)

Role: lead

NCT00038428Phase 2Completed

Phase 2 Study of TLK286 in Platinum Resistant Advanced Epithelial Ovarian Cancer

Role: lead

NCT00047801Phase 1Completed

Phase 1-2a Dose-Ranging Study of TLK286 in Combination With Docetaxel in Platinum-Resistant Non-Small Cell Lung Cancer

Role: lead

NCT00051948Phase 1Completed

TLK286 in Combination With Paraplatin (Carboplatin) in Recurrent Ovarian Cancer

Role: lead

NCT00040638Phase 2Completed

Phase 2 Study of TLK286 Administered Weekly in Advanced Non-Small Cell Lung Cancer

Role: lead

NCT00077883Phase 1Completed

TLK286 (Telcyta) in Combination With Cisplatin for Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

Role: lead

NCT00035841Phase 2Completed

Phase 2 Study of TLK286 in Metastatic Breast Cancer

Role: lead

NCT00052065Phase 1Completed

TLK286 in Combination With Doxil in Platinum Refractory or Resistant Ovarian Cancer

Role: lead

NCT00057720Phase 3Completed

TLK286 (Telcyta) vs. Doxil/Caelyx or Hycamtin in Platinum Refractory or Resistant Ovarian Cancer

Role: lead

NCT00035867Phase 1Completed

Study of TLK199 HCl Liposomes for Injection in Myelodysplastic Syndrome

Role: lead