Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 90/100

Failure Rate

35.7%

5 terminated/withdrawn out of 14 trials

Success Rate

64.3%

-22.2% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 9 completed trials have results

Key Signals

Enrollment Performance

Analytics

Phase 2
14(100.0%)
14Total
Phase 2(14)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT01417663Phase 2Completed

Effects of Exercise Training and AGE-crosslink Breaker on Cardiovascular Structure and Function

Role: collaborator

NCT00045981Phase 2Completed

The SAPPHIRE Study (Systolic And Pulse Pressure Hemodynamic Improvement By Restoring Elasticity)

Role: lead

NCT00089713Phase 2Terminated

Systolic Pressure Efficacy and Safety Trial of Alagebrium (SPECTRA)

Role: lead

NCT00516646Phase 2Completed

The BENEFICIAL Study: Evaluating the Efficacy and Safety of Alagebrium (ALT-711) in Patients With Chronic Heart Failure

Role: lead

NCT00043836Phase 2Completed

The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure

Role: lead

NCT00277875Phase 2Completed

STRETCH Study: Effect of Distensibility on Endothelial-Dependent Vasoreactivity in Patients With ISH

Role: lead

NCT00045994Phase 2Completed

The SILVER Study: Systolic Hypertension Interaction With Left Ventricular Remodeling

Role: lead

NCT00782613Phase 2Terminated

Efficacy and Safety of Topical ALT-2074 (SYI-2074) for Treatment of Chronic Plaque Psoriasis

Role: lead

NCT00662116Phase 2Terminated

Beginning a Randomized Evaluation of the AGE Breaker Alagebrium in Diastolic Heart Failure (BREAK-DHF-I)

Role: lead

NCT00739687Phase 2Terminated

Safety & Efficacy of ALT-711 (Alagebrium) in Chronic Heart Failure

Role: lead

NCT00557518Phase 2Terminated

Study of Alagebrium in Patients With Insulin-Dependent Type 1 Diabetes and Microalbuminuria

Role: lead

NCT00320502Phase 2Completed

A Phase 2 Study to Determine the Effects of BXT-51072 in Diabetic Patients Undergoing Angioplasty (PCI)

Role: lead

NCT00491543Phase 2Completed

Evaluation of ALT-2074 in Subjects With Type-2 Diabetes, Haptoglobin Type 2-2 Genotype and Coronary Artery Disease

Role: lead

NCT00302250Phase 2Completed

The STRETCH Study: Distensibility on Endothelial-Dependent Vasoreactivity in Subjects With Systolic Hypertension

Role: lead

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