Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

0.0%

0 terminated/withdrawn out of 16 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

29%

2 of 7 completed trials have results

Key Signals

5 recruiting2 with results

Enrollment Performance

Analytics

Phase 1
9(56.3%)
Phase 2
7(43.8%)
16Total
Phase 1(9)
Phase 2(7)

Activity Timeline

Global Presence

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Clinical Trials (16)

Showing 16 of 16 trials
NCT07002320Phase 1Recruiting

Investigating SX-682 in Combination With Apalutamide in Metastatic Castration-resistant Prostate Cancer

Role: collaborator

NCT07322341Phase 2Not Yet Recruiting

SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer

Role: collaborator

NCT04599140Phase 1Active Not Recruiting

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

Role: collaborator

NCT03161431Phase 1Active Not Recruiting

SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab

Role: lead

NCT04245397Phase 1Recruiting

Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

Role: lead

NCT06228053Phase 2Recruiting

Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

Role: lead

NCT05570825Phase 2Recruiting

SX-682 With Pembrolizumab for the Treatment of Metastatic or Recurrent Stage IIIC or IV Non-Small Cell Lung Cancer

Role: collaborator

NCT05604560Phase 2Active Not Recruiting

A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer

Role: collaborator

NCT04477343Phase 1Recruiting

A Study to Evaluate the Safety and Tolerability of SX-682 in Combination With Nivolumab as a Maintenance Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Role: collaborator

NCT03431974Phase 2Completed

Once-Weekly Oral Aminopterin for the Treatment of Subjects With Moderate-To-Severe Psoriasis

Role: lead

NCT04683926Phase 1Completed

A Randomized Study Investigating Oral Desmetramadol Dose Proportionality and Food Effect In Normal Human Subjects

Role: lead

NCT03664921Phase 2Completed

Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy

Role: lead

NCT00937027Phase 1Completed

Aminopterin Pharmacokinetic Study In Moderate to Severe Psoriasis

Role: lead

NCT03312777Phase 1Completed

Omnitram Pharmacokinetic and Analgesic Study Following CY2D6 Inhibition With Paroxetine In Healthy Volunteers

Role: lead

NCT01724931Phase 2Completed

Aminopterin Dose Finding Treatment for Methotrexate-Naïve Rheumatoid Arthritis

Role: lead

NCT02205554Phase 1Completed

Omnitram Pharmacokinetic Study In Healthy Volunteers

Role: lead

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