Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

10.9%

5 terminated/withdrawn out of 46 trials

Success Rate

86.5%

-0.0% vs industry average

Late-Stage Pipeline

35%

16 trials in Phase 3/4

Results Transparency

9%

3 of 32 completed trials have results

Key Signals

3 with results

Enrollment Performance

Analytics

Phase 1
23(59.0%)
Phase 4
12(30.8%)
Phase 3
4(10.3%)
39Total
Phase 1(23)
Phase 4(12)
Phase 3(4)

Activity Timeline

Global Presence

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Clinical Trials (46)

Showing 20 of 46 trials
NCT02354209Unknown

Targeted Clinical Strategies and Low Level Viraemia (LLV) in Boosted Protease Inhibitor Therapy

Role: lead

NCT03094507Phase 1Completed

The Pharmacokinetics of Dolutegravir, Darunavir/Cobocistat When Co-administered in Healthy Volunteers

Role: lead

NCT02098837Phase 4Completed

Cardiovascular Risk in HIV Patients Switching From a Boosted Protease Inhibitor (PI) to Dolutegravir (DTG)

Role: lead

NCT02509195Phase 4Completed

SSAT064: Pharmacokinetics of Abacavir/Lamivudine/Dolutegravir in HIV Patients of 60 Years and Over

Role: lead

NCT03152942Phase 1Unknown

Progesterone and Aminophylline for the Prevention of Preterm Labour

Role: lead

NCT02697851Phase 1Terminated

Pharmacokinetic Effect of Evotaz/Microgynon Co-administration

Role: lead

NCT02383953Unknown

SSAT 054: Non Genetic Factors in the Pathogenesis of IBD in Twins

Role: lead

NCT02499874Phase 1Completed

SSAT063- Pharmacokinetics of Efavirenz 400 mg Once Daily During Pregnancy in HIV-1 Infected Women

Role: lead

NCT02529059Phase 4Completed

SSAT058: Atripla to Eviplera Switch in Patients Without Central Nervous System Symptoms

Role: lead

NCT03253757Unknown

PrEP Impact Trial: A Pragmatic Health Technology Assessment of PrEP and Implementation

Role: lead

NCT01701882Phase 3Completed

A Pilot Study to Assess the Feasibility of Switching, Individuals Receiving Atripla With Continuing Central Nervous System (CNS) Toxicity, to a Fixed Dose Combination of Tenofovir/Emtricitabine/Rilpivirine

Role: lead

NCT02351908Phase 4Completed

Renal Integrase Study

Role: lead

NCT01286623Completed

The Pharmacology/Aging Clinic

Role: lead

NCT01275443Phase 1Completed

Study in Healthy Volunteers of the Safety and Metabolism of Different Doses of the Anti-HIV Drug TMC278LA.

Role: lead

NCT02832778Phase 1Unknown

Pharmacokinetics of Efavirenz in the Presence of Rifampicin and Isoniazid

Role: lead

NCT01736761Phase 4Completed

A Phase IV, Open-label Single-arm Study Investigating the Pharmacokinetics and Pharmacodynamics of the Antiretroviral Combination of Rilpivirine and Ritonavirboosted Darunavir in Therapy-naive HIV-1 Infected Patients.

Role: lead

NCT02006745Phase 3Completed

Open Label Trial of PEG-IFN, RBV & TVR vs. PEG-IFN & RBV Alone in Tx of HCV-1 in HIV-1 Co-infected Patients (CHAT)

Role: lead

NCT02631473Phase 1Suspended

PK of Efavirenz & Lopinavir Nano-formulations in Healthy Volunteers

Role: lead

NCT02219217Phase 1Completed

SSAT061: PK of DTG and EVT/COBI in Healthy Volunteers

Role: lead

NCT02589158Phase 1Completed

SSAT067 PK of Atazanavir/Cobicistat and Darunavir/Cobicistat

Role: lead