Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

8.6%

42 terminated/withdrawn out of 489 trials

Success Rate

86.6%

-0.0% vs industry average

Late-Stage Pipeline

5%

24 trials in Phase 3/4

Results Transparency

34%

92 of 271 completed trials have results

Key Signals

101 recruiting92 with results35 terminated7 withdrawn

Enrollment Performance

Analytics

N/A
95(31.1%)
Phase 2
92(30.2%)
Phase 1
90(29.5%)
Phase 3
21(6.9%)
Early Phase 1
4(1.3%)
Phase 4
3(1.0%)
305Total
N/A(95)
Phase 2(92)
Phase 1(90)
Phase 3(21)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (489)

Showing 20 of 489 trials
NCT05550948Not ApplicableCompleted

Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer

Role: lead

NCT04733534Phase 2Active Not Recruiting

An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer

Role: lead

NCT07805278Recruiting

A Registry of Cases of Spinal Muscular Atrophy

Role: lead

NCT07594392Recruiting

Clinical Assessment and Targeted Imaging to Characterize High-Risk Atherosclerotic Cardiovascular Disease of Survivors in SJLIFE

Role: lead

NCT07830134Not ApplicableRecruiting

Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real Time Hemodynamic Neurofeedback

Role: lead

NCT07790913Phase 2Not Yet Recruiting

Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma

Role: lead

NCT07834710Not Yet Recruiting

Using Bioimpedance Analysis to Monitor Fluid Status in Children

Role: lead

NCT02792582Phase 2Active Not Recruiting

A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection

Role: lead

NCT01857934Phase 2Completed

Therapy for Children With Advanced Stage Neuroblastoma

Role: lead

NCT05955261Phase 2Recruiting

A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia

Role: lead

NCT06819475Not ApplicableRecruiting

Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors

Role: lead

NCT05932914Not Yet Recruiting

Liver Biopsy Following Gene Therapy For Hemophilia

Role: lead

NCT07008027Not Yet Recruiting

Real World Asparaginase Therapy Toxicity

Role: lead

NCT03597594Phase 1Active Not Recruiting

Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)

Role: lead

NCT04558736Phase 2Recruiting

Haploidentical HCT for Severe Aplastic Anemia

Role: lead

NCT07531498Recruiting

Muscle Aging Phenotypes in Childhood Cancer Survivors

Role: lead

NCT03849651Phase 2Active Not Recruiting

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

Role: lead

NCT04065776Not ApplicableActive Not Recruiting

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

Role: lead

NCT05535166Phase 2Recruiting

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

Role: lead

NCT06646640Recruiting

Long Term Follow-Up Study for Individuals With Hemoglobin Disorders After Hematopoietic Cell Transplant or Gene Therapy

Role: lead