Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

43.4%

36 terminated/withdrawn out of 83 trials

Success Rate

53.8%

-32.7% vs industry average

Late-Stage Pipeline

23%

19 trials in Phase 3/4

Results Transparency

93%

39 of 42 completed trials have results

Key Signals

1 recruiting39 with results30 terminated6 withdrawn

Enrollment Performance

Analytics

Phase 2
37(45.1%)
Phase 1
26(31.7%)
Phase 3
19(23.2%)
82Total
Phase 2(37)
Phase 1(26)
Phase 3(19)

Activity Timeline

Global Presence

Loading network data...

Clinical Trials (83)

Showing 20 of 83 trials
NCT05378763Phase 3Suspended

A Study of Poziotinib in Previously Treated Participants With Locally Advanced or Metastatic NSCLC Harboring HER2 Exon 20 Mutations

Role: lead

NCT04570423Phase 2Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

Role: lead

NCT03066206Phase 2Terminated

Poziotinib in EGFR Exon 20 Mutant Advanced NSCLC

Role: collaborator

NCT02879643Phase 1Completed

Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy

Role: collaborator

NCT02909036Phase 1Active Not Recruiting

Study of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant.

Role: collaborator

NCT01478542Phase 3Completed

OPTIMAL>60 / DR. CHOP, Improvement of Therapy of Elderly Patients with CD20+ DLBCL Using Rituximab Optimized and Liposomal Vincristine

Role: collaborator

NCT04187898Phase 1Completed

Open-Label, Phase 1 Study to Evaluate Duration of Severe Neutropenia After Same-Day Dosing of Eflapegrastim in Patients With Breast-Cancer

Role: lead

NCT04402008Phase 1Terminated

Study of Poziotinib in Japanese Patients With NSCLC

Role: lead

NCT03318939Phase 2Terminated

Phase 2 Study of Poziotinib in Participants With NSCLC Having EGFR or HER2 Exon 20 Insertion Mutation

Role: lead

NCT04172597Phase 2Terminated

A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies

Role: lead

NCT03744715Phase 2Terminated

A Study to Allow Continued Dosing and/or Follow-up of Patients Who Have Had Previous Exposure to Poziotinib

Role: lead

NCT01336933Phase 2Completed

Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma

Role: collaborator

NCT02994784Phase 2Terminated

Propylene Glycol-Free Melphalan Hydrochloride (Evomela) in AL Amyloidosis Patients

Role: collaborator

NCT02137759Phase 2Unknown

MRSI to Predict Response to RT/TMZ ± Belinostat in GBM

Role: collaborator

NCT02257242Phase 1Completed

Vincristine Sulfate Liposome Injection (Marqibo®), Bendamustine and Rituximab-Phase I Trial in Indolent B-cell Lymphoma

Role: collaborator

NCT01811368Phase 2Unknown

Zevalin Before Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma

Role: collaborator

NCT01319981Phase 2Completed

Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia

Role: collaborator

NCT01724866Phase 2Completed

Phase 2 Study of SPI-2012 or Pegfilgrastim for the Management of Neutropenia in Participants With Breast Cancer

Role: lead

NCT02519270Phase 1Terminated

Phase 1, Dose-Escalation Study of IGN002 in NHL Subjects

Role: lead

NCT02659514Phase 2Completed

Study of Poziotinib in Participants With HER2-Positive Metastatic Breast Cancer

Role: lead