Shire
445
2
8
357
Key Highlights
Risk & Performance
Pipeline Risk Assessment
Pipeline Risk Assessment
Based on historical performance
Moderate Risk
Score: 35/100
15.1%
67 terminated/withdrawn out of 445 trials
84.2%
-2.3% vs industry average
50%
224 trials in Phase 3/4
84%
301 of 357 completed trials have results
Key Signals
Enrollment Performance
Analytics
Activity Timeline
Global Presence
Clinical Trials (445)
An Efficacy and Safety Study of HGT-1110 in Participants With Metachromatic Leukodystrophy
Role: lead
A Study of Intrathecal SHP611 in Children With Metachromatic Leukodystrophy
Role: lead
A Study of TAK-503 in Children and Teenagers With Attention Deficit Hyperactivity Disorder (ADHD)
Role: lead
A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura
Role: collaborator
Long-term Evaluation on Height and Weight in Patients With MPS II Who Started Treatment at < 6 Years of Age
Role: lead
Efficacy METAZYM for the Treatment Metachromatic Leukodystrophy Treated With Hematopoietic Stem Cell Transplantation
Role: collaborator
A One Visit Follow Up of Adults With Fabry Disease Who Started Long-term Enzyme Replacement Therapy As Children
Role: collaborator
SC-PEG Asparaginase vs. Oncaspar in Pediatric Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma
Role: collaborator
A Survey to Assess Participants' and Physicians' Knowledge, Attitudes and Behavior When Using NATPARA
Role: lead
Registry for Participants With Short Bowel Syndrome
Role: lead
Gaucher Disease Outcome Survey (GOS)
Role: lead
A Study of Replagal in Children and Adults With Fabry Disease in India
Role: lead
A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia
Role: collaborator
A French Protocol for the Treatment of Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents
Role: collaborator
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single Oral Dose of Maribavir Administered in Healthy Japanese Participants Compared With Matched, Healthy, Non-Hispanic, Caucasian Participants and to Assess Dose-Proportionality of 3 Doses of Maribavir in Japanese Participants
Role: lead
Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome
Role: collaborator
A Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension Formulations of Maribavir to the Current Maribavir Tablet Formulation Administered in Healthy Adult Participants
Role: lead
A Study of Lanadelumab in Persons With Hereditary Angioedema (HAE) Type I or II
Role: lead
Efficacy and Safety Eval of Guanfacine Hydrochloride in Combination With Psychostimulants in Adults (18-65).
Role: collaborator
Study of Long Term Safety and Clinical Outcomes of Idursulfase IT and Elaprase Treatment in Pediatric Participants Who Have Completed Study HGT-HIT-094
Role: lead