Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 50/100

Failure Rate

5.3%

7 terminated/withdrawn out of 131 trials

Success Rate

80.0%

-6.5% vs industry average

Late-Stage Pipeline

19%

25 trials in Phase 3/4

Results Transparency

7%

2 of 28 completed trials have results

Key Signals

29 recruiting2 with results5 withdrawn

Enrollment Performance

Analytics

Phase 1
55(42.3%)
Phase 2
49(37.7%)
Phase 3
25(19.2%)
Early Phase 1
1(0.8%)
130Total
Phase 1(55)
Phase 2(49)
Phase 3(25)
Early Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (131)

Showing 20 of 131 trials
NCT07739758Phase 3Not Yet Recruiting

A Study of YL201 in Combination With Serplulimab in Participants With Treatment-naïve Extensive-stage Small Cell Lung Cancer

Role: collaborator

NCT07518043Phase 1Recruiting

A Study of HLX18 vs. OPDIVO® in Multiple Resected Solid Tumors

Role: lead

NCT07253142Phase 2Recruiting

A Phase II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Subjects With Advanced Lung Cancer

Role: lead

NCT07416695Phase 1Recruiting

A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HLX3901 in Patients With Advanced SCLC or NEC

Role: lead

NCT07473726Phase 1Recruiting

A Phase I Clinical Study to Evaluate the Safety, Tolerability, and PK of HLX48 in Advanced/Metastatic Solid Tumors

Role: lead

NCT07269782Phase 2Recruiting

A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as Neoadjuvant Therapy in Subjects With NSCLC

Role: lead

NCT07459751Phase 2Recruiting

A Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43 Monotherapy or HLX43 in Combination With HLX07 Versus Docetaxel in Advanced or Metastatic Squamous Non-Small Cell Lung Cancer

Role: lead

NCT06115642Phase 1Enrolling By Invitation

A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX43 in Advanced/Metastatic Solid Tumors

Role: lead

NCT07541534Phase 1Recruiting

A Phase I Clinical Study of HLX316 in Participants With Advanced/Metastatic Solid Tumors

Role: lead

NCT07601620Phase 1Not Yet Recruiting

A Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of HLX319 vs. EU-Phesgo® in the Neoadjuvant Therapy of HER2-Positive Early or Locally Advanced Breast Cancer

Role: lead

NCT07477587Phase 1Recruiting

A Study to Compare the PK Characteristics, Safety, Tolerability, and Immunogenicity of HLX15-SC With DARZALEX FASPRO® in Combination With Lenalidomide and Dexamethasone (Rd) in Transplant-ineligible Patients With Newly Diagnosed Multiple Myeloma

Role: lead

NCT06812260Phase 2Active Not Recruiting

A Single-arm, Open-label, Phase II Study to Evaluate Efficacy, Safety and Pharmacokinetics of HLX10 + Chemotherapy in Patients With ES-SCLC

Role: lead

NCT06769113Phase 2Recruiting

A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC Failed or Intolerance to Standard Therapy

Role: lead

NCT07160335Phase 1Recruiting

A Phase I Clinical Study to Evaluate the PK Profile, Efficacy, Safety and Immunogenicity of HLX17 vs. Keytruda® in Multiple Resected Solid Tumors

Role: lead

NCT07543471Phase 1Not Yet Recruiting

A Phase I Multicentre Randomized Double-Blind Parallel-Controlled Study of HLX05-N vs. ERBITUX® in Metastatic Colorectal Cancer

Role: lead

NCT06769152Phase 2Recruiting

A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Patients With Advanced Gynecological Malignant Tumors

Role: lead

NCT07533708Phase 1Not Yet Recruiting

A Phase I Clinical Study of HLX3902 in Patients With mCRPC and Other Advanced Tumours

Role: lead

NCT07495930Phase 1Not Yet Recruiting

Pharmacokinetic Characteristics, Safety, and Immunogenicity of HLX319 Compared With EU-Phesgo®

Role: lead

NCT07487519Phase 2Not Yet Recruiting

Phase II Study of HLX43 Monotherapy or Combined With Immune Checkpoint Inhibitors in Patients With Locally Advanced, Recurrent, or Metastatic Triple-negative Breast Cancer.

Role: lead

NCT07294508Phase 2Recruiting

A Study to Evaluate HLX22 in Combination With HLX87 in Patients With HER2-Positive Recurrent or Metastatic Breast Cancer

Role: lead