Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

20.0%

2 terminated/withdrawn out of 10 trials

Success Rate

50.0%

-36.5% vs industry average

Late-Stage Pipeline

20%

2 trials in Phase 3/4

Results Transparency

50%

1 of 2 completed trials have results

Key Signals

4 recruiting1 with results

Enrollment Performance

Analytics

Phase 1
8(80.0%)
Phase 3
2(20.0%)
10Total
Phase 1(8)
Phase 3(2)

Activity Timeline

Global Presence

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Clinical Trials (10)

Showing 10 of 10 trials
NCT05921760Phase 1Terminated

Ivosidenib, Nivolumab, and Ipilimumab Combination in Previously Treated Subjects With Nonresectable or Metastatic IDH1 Mutant Cholangiocarcinoma

Role: lead

NCT06563804Phase 1Terminated

A Study to Evaluate S227928 as a Single Agent and in Combination With Venetoclax in Patients With R/R AML, MDS/AML, or CMML

Role: lead

NCT06116136Phase 1Active Not Recruiting

A Study to Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers.

Role: lead

NCT06162572Phase 1Active Not Recruiting

Phase 1b/2 Platform Study of Select Immunotherapy Combinations in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)

Role: lead

NCT06188702Phase 1Recruiting

S095035 as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of MTAP

Role: lead

NCT07006688Phase 1Recruiting

A Study of an IDH1m Inhibitor in Participants With IDH1-Mutated Malignancies and Hepatic or Renal Impairment

Role: lead

NCT06465953Phase 3Recruiting

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

Role: collaborator

NCT06127407Phase 3Recruiting

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

Role: lead

NCT05159388Phase 1Completed

A Study of PRS-344/S095012 (PD-L1x4-1BB Bispecific Antibody-Anticalin Fusion) in Patients With Solid Tumors

Role: lead

NCT05843708Phase 1Completed

A Phase 1, Open-Label Study to Evaluate the Effect of a Low-Fat Meal and Multiple Doses of Ciprofloxacin on the Pharmacokinetics of Vorasidenib in Healthy Subjects

Role: lead

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