Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 85/100

Failure Rate

25.0%

4 terminated/withdrawn out of 16 trials

Success Rate

55.6%

-30.9% vs industry average

Late-Stage Pipeline

6%

1 trials in Phase 3/4

Results Transparency

0%

0 of 5 completed trials have results

Key Signals

Enrollment Performance

Analytics

N/A
6(50.0%)
Phase 1
3(25.0%)
Phase 2
2(16.7%)
Phase 3
1(8.3%)
12Total
N/A(6)
Phase 1(3)
Phase 2(2)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (16)

Showing 16 of 16 trials
NCT04603014Phase 2Active Not Recruiting

Interdialytic Peritoneal UltraFiltration in HemoDialysis Patients

Role: collaborator

NCT04326946Active Not Recruiting

International Alfapump Cohort Study

Role: lead

NCT05965934Phase 1Unknown

Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0

Role: lead

NCT05780086Phase 1Unknown

Safety of and Tolerability to a Sodium-free Peritoneal Dialysis Solution

Role: collaborator

NCT03973866Not ApplicableUnknown

Alfapump® System in the Treatment of Refractory or Recurrent Ascites (POSEIDON Study)

Role: lead

NCT04882358Not ApplicableUnknown

Safety & Feasibility of DSR TherApy in Heart FAiluRe pAtients With Persistent Congestion

Role: lead

NCT04116034Not ApplicableCompleted

Alfapump Direct Sodium Removal (DSR) Feasibility Study

Role: lead

NCT03032211Phase 1Withdrawn

Optimal Balance Alfapump® System Feasibility Study

Role: lead

NCT01532427Completed

ALFApump System Post Marketing Surveillance Registry

Role: lead

NCT04076566Withdrawn

Malignant Ascites Alfapump® Study

Role: lead

NCT02448160Not ApplicableTerminated

Alfapump-albumin Replacement Therapy

Role: lead

NCT03200106Completed

Retrospective Study in the Use of the Alfapump and the Treatment of Malignant Ascites

Role: lead

NCT02400164Not ApplicableCompleted

A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effectiveness of an Automatic Low Flow (A)Scites (Alfa) Pump (I)n Patients With (C)Irrhosis and Refractory or Recurrent Ascites

Role: lead

NCT01528410Phase 3Completed

ALFApump System Versus Standard of Care in Ascites Treatment

Role: lead

NCT01952327Not ApplicableTerminated

Investigation Into the Automated Drainage of Recurrent Effusions From the Pleural Space in Thoracic Malignancy.

Role: lead

NCT01438970Phase 2Unknown

Effects of Treatment of Ascites by the ALFApump System on Renal and Circulatory Function

Role: lead

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