Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 15/100

Failure Rate

10.5%

2 terminated/withdrawn out of 19 trials

Success Rate

88.9%

+2.4% vs industry average

Late-Stage Pipeline

37%

7 trials in Phase 3/4

Results Transparency

69%

11 of 16 completed trials have results

Key Signals

1 recruiting11 with results

Enrollment Performance

Analytics

Phase 3
7(38.9%)
Phase 1
6(33.3%)
Phase 2
5(27.8%)
18Total
Phase 3(7)
Phase 1(6)
Phase 2(5)

Activity Timeline

Global Presence

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Clinical Trials (19)

Showing 19 of 19 trials
NCT05178862Phase 3Terminated

A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole

Role: lead

NCT06954493Phase 1Completed

Pharmacokinetic Study in Healthy Lactating Women Exposed to Ibrexafungerp

Role: lead

NCT03059992Phase 3Completed

Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment

Role: lead

NCT03672292Phase 2Terminated

Evaluate Safety and Efficacy of the Coadministration of Ibrexafungerp With Voriconazole in Patients With Invasive Pulmonary Aspergillosis

Role: lead

NCT05908682Recruiting

Safety of Pregnant Subjects Exposed to Ibrexafungerp Including Infant Outcomes

Role: lead

NCT05399641Phase 3Completed

Ibrexafungerp for the Treatment of Complicated Vulvovaginal Candidiasis

Role: lead

NCT03363841Phase 3Completed

Open-Label Study to Evaluate the Efficacy and Safety of Oral Ibrexafungerp (SCY-078) in Patients With Candidiasis Caused by Candida Auris (CARES)

Role: lead

NCT02244606Phase 2Completed

Oral Ibrexafungerp (SCY-078) vs Standard-of-Care Following IV Echinocandin in the Treatment of Invasive Candidiasis

Role: lead

NCT05668429Phase 1Completed

ADME Study of [14^C]-Ibrexafungerp in Healthy Male Subjects

Role: lead

NCT04029116Phase 3Completed

Phase 3 Study of Oral Ibrexafungerp (SCY-078) Vs. Placebo in Subjects With Recurrent Vulvovaginal Candidiasis (VVC)

Role: lead

NCT03987620Phase 3Completed

Efficacy and Safety of Oral Ibrexafungerp (SCY-078) vs. Placebo in Subjects With Acute Vulvovaginal Candidiasis

Role: lead

NCT03734991Phase 3Completed

Efficacy and Safety of Oral Ibrexafungerp (SCY-078) vs. Placebo in Subjects With Acute Vulvovaginal Candidiasis (VANISH 303)

Role: lead

NCT03253094Phase 2Completed

Dose-Finding Study of Oral Ibrexafungep (SCY-078) vs. Oral Fluconazole in Subjects With Acute Vulvovaginal Candidiasis

Role: lead

NCT04092751Phase 1Completed

Study to Evaluate the Effect of SCY-078 (Ibrexafungerp) on the PK of Pravastatin in Healthy Subjects

Role: lead

NCT04092725Phase 1Completed

Study to Evaluate the Effect of SCY-078 on the PK of Dabigatran in Healthy Subjects

Role: lead

NCT04307082Phase 1Completed

ADME Study of [14C]-Ibrexafungerp in Healthy Male Subjects

Role: lead

NCT02679456Phase 2Completed

Safety and Efficacy of Oral Ibrexafungerp (SCY-078) vs. Oral Fluconazole in Subjects With Vulvovaginal Candidiasis

Role: lead

NCT01265511Phase 2Completed

Study of SCY-635, Pegasys and Copegus in Hepatitis C

Role: lead

NCT01290965Phase 1Completed

Safety, PK and Efficacy of 15 Days of SCY-635 Treatment in Hepatitis C Patients

Role: lead

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