Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

17.1%

6 terminated/withdrawn out of 35 trials

Success Rate

82.4%

-4.2% vs industry average

Late-Stage Pipeline

26%

9 trials in Phase 3/4

Results Transparency

43%

12 of 28 completed trials have results

Key Signals

12 with results

Enrollment Performance

Analytics

Phase 2
17(50.0%)
Phase 1
8(23.5%)
Phase 3
6(17.6%)
Phase 4
3(8.8%)
34Total
Phase 2(17)
Phase 1(8)
Phase 3(6)
Phase 4(3)

Activity Timeline

Global Presence

Loading network data...

Clinical Trials (35)

Showing 20 of 35 trials
NCT04704609Active Not Recruiting

Imaging Quantification of Inflammation (IQI)

Role: collaborator

NCT05376176Phase 2Completed

A Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared With Vehicle in Subjects With Fuchs Endothelial Corneal Dystrophy (FECD)

Role: lead

NCT05665387Phase 2Completed

Study Assessing the Efficacy and Safety of STN1013600 Ophthalmic Solution 0.1% and 0.3% Compared With Placebo in Subjects With Presbyopia

Role: lead

NCT03711929Phase 3Terminated

LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the Eye

Role: lead

NCT01280669Phase 2Withdrawn

Intravitreal Sirolimus as Therapeutic Approach to Uveitis

Role: collaborator

NCT03691649Phase 3Completed

A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 3 Study

Role: lead

NCT03697811Phase 3Completed

DE-117 Spectrum 5 Study

Role: lead

NCT03691662Phase 3Completed

A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 4 Study

Role: lead

NCT04742283Phase 2Completed

Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Role: lead

NCT03211234Phase 2Completed

Study Assessing the Efficacy and Safety of Intravitreal Injections of DE-122 in Combination With Lucentis® Compared to Lucentis® Monotherapy in Wet Age-related Macular Degeneration Subjects

Role: lead

NCT03216902Phase 2Completed

A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study

Role: lead

NCT03858894Phase 2Completed

Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6

Role: lead

NCT02251938Phase 3Completed

A Phase IIIb, Multinational, Multicenter, Open-Label Extension Study Assessing the Long-Term Safety of PRN Intravitreal Injections of DE-109 in Subjects With Non-Infectious Uveitis of the Posterior Segment of the Eye Who Have Participated in the SAKURA Development Program

Role: lead

NCT02555306Phase 1Completed

A Phase I/II Safety, Tolerability, Immunogenicity, and Bioactivity Study of DE-122 Injectable Solution for Refractory Exudative Age-related Macular Degeneration

Role: lead

NCT01358266Phase 3Completed

Study Assessing Double-masked Uveitis Treatment

Role: lead

NCT02401945Phase 2Completed

A Safety and Efficacy Study of DE-120 Injectable Solution for Age-related Macular Degeneration

Role: lead

NCT01654484Phase 1Completed

A Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Patients With POAG or OHT

Role: lead

NCT02022501Phase 1Completed

A Phase I/II Safety Study of DE-120 Injectable Solution for Age-related Macular Degeneration

Role: lead

NCT02179008Phase 2Completed

Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension

Role: lead

NCT01868126Phase 2Completed

Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension

Role: lead