Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

0.0%

0 terminated/withdrawn out of 12 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

50%

2 of 4 completed trials have results

Key Signals

3 recruiting2 with results

Enrollment Performance

Analytics

Phase 1
9(75.0%)
Phase 2
2(16.7%)
Early Phase 1
1(8.3%)
12Total
Phase 1(9)
Phase 2(2)
Early Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT05887882Phase 1Suspended

Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Pediatric Brain Tumors

Role: lead

NCT05465174Phase 2Recruiting

Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults

Role: lead

NCT04732065Phase 1Recruiting

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

Role: lead

NCT07447076Phase 2Not Yet Recruiting

Study of Novel Therapies for Young People With Recurrent/Progressive Atypical Teratoid Rhabdoid Tumor (ATRT)

Role: lead

NCT07389278Phase 1Not Yet Recruiting

Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG)

Role: lead

NCT07346157Phase 1Not Yet Recruiting

Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease

Role: lead

NCT03893487Early Phase 1Active Not Recruiting

Fimepinostat in Treating Brain Tumors in Children and Young Adults

Role: lead

NCT04323046Phase 1Recruiting

Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

Role: lead

NCT02960230Phase 1Completed

H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas

Role: lead

NCT02962167Phase 1Completed

Modified Measles Virus (MV-NIS) for Children and Young Adults With Recurrent Medulloblastoma or Recurrent ATRT

Role: lead

NCT03086616Phase 1Completed

CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With Diffuse Intrinsic Pontine Glioma (DIPG) (PNOC 009)

Role: lead

NCT03566199Phase 1Completed

MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma

Role: lead

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