Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

12.9%

8 terminated/withdrawn out of 62 trials

Success Rate

84.6%

-1.9% vs industry average

Late-Stage Pipeline

24%

15 trials in Phase 3/4

Results Transparency

66%

29 of 44 completed trials have results

Key Signals

3 recruiting29 with results7 terminated

Enrollment Performance

Analytics

Phase 1
23(38.3%)
Phase 2
22(36.7%)
Phase 3
15(25.0%)
60Total
Phase 1(23)
Phase 2(22)
Phase 3(15)

Activity Timeline

Global Presence

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Clinical Trials (62)

Showing 20 of 62 trials
NCT07543744Phase 1Recruiting

A Comparative Study of Pharmacokinetics, Safety, and Immunogenicity of RPH-030 and Vectibix® in Patients With Metastatic Colorectal Cancer With Wild-type RAS as First-line Therapy in Combination With FOLFIRI

Role: lead

NCT07517575Phase 2Recruiting

Pharmacokinetics, Efficacy and Safety of Olokizumab In Patients With Juvenile Idiopathic Arthritis

Role: collaborator

NCT07435311Phase 1Completed

A Phase I Comparative Study of Pharmacokinetics, Safety, and Efficacy of RPH-002 and Erbitux® in Unresectable Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma

Role: lead

NCT07435324Phase 3Active Not Recruiting

A Comparative Study of Efficacy and Safety of RPH-002 and Erbitux® in Unresectable Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma

Role: lead

NCT07386938Phase 3Active Not Recruiting

A Study of the Efficacy, Safety and Pharmacokinetics of RPH-051 and Perjeta® in Combination With Trastuzumab and Docetaxel as the 1st Line Therapy in Patients With HER2-positive Breast Cancer

Role: lead

NCT06440746Phase 2Recruiting

Efficacy and Safety of Olokizumab in Patients With Progressive Fibrosing Interstitial Lung Diseases

Role: collaborator

NCT05673902Phase 3Active Not Recruiting

Study of the Safety and Efficacy of RPH-104 in Preventing Recurrences in Patients With Idiopathic Recurrent Pericarditis

Role: collaborator

NCT04463251Phase 2Completed

Study to Evaluate the Effect on Parameters of Systemic Inflammation and Disease Outcomes and Safety of RPH-104 in Subjects With Acute ST-elevation Myocardial Infarction

Role: collaborator

NCT06320353Phase 3Active Not Recruiting

Study сomparing the Efficacy and Safety of RPH-075 and Keytruda® in Patients With Unresectable or Metastatic Skin Melanoma

Role: lead

NCT06307093Phase 1Active Not Recruiting

Study Comparing the Pharmacokinetics, Safety, and Efficacy of RPH-075 and Keytruda® in Patients With Malignant Neoplasms

Role: lead

NCT05773170Completed

Efficacy and Safety Evaluation of Refralon®, Concentrate for Solution for Intravenous Injection in Patients With Paroxysmal and Persistent Atrial Fibrillation and Flutter

Role: lead

NCT03551210Phase 3Completed

Efficacy and Safety of Nemonoxacin vs Levofloxacin in Adult Patients With Community-Acquired Pneumonia

Role: lead

NCT05187793Phase 3Unknown

Study of Efficacy of Different Treatment Regimens of Olokizumab

Role: lead

NCT05196477Completed

Study of the Outcomes of Olokizumab Therapy in Hospitalized Patients With SARS-CoV-2 (COVID-19) Infection

Role: lead

NCT04501783Phase 3Completed

Study of Efficacy and Safety of TL-FVP-t vs. SOC in Patients With Mild to Moderate COVID-19

Role: lead

NCT04246723Phase 2Completed

Efficacy and Safety of All-Oral Combination of Narlaprevir/Ritonavir and Sofosbuvir in Treatment-naïve Patients With Chronic Hepatitis C Genotype 1

Role: lead

NCT04760730Phase 1Completed

Safety and Immunogenicity Study in Adults of AZD1222 and rAd26-S Administered as Heterologous Prime Boost Regimen for the Prevention of Coronavirus Disease 2019 (COVID-19)

Role: lead

NCT04067492Phase 2Terminated

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Evaluation of RPH-104 Administered at Different Doses to Patients With Acute Gout Attack

Role: lead

NCT04686773Phase 2Completed

Open-label, Non-randomized, Non-comparative, Phase II Study of Safety and Immunogenicity of Combination of AZD1222 and rAd26-S for COVID-19 Prevention

Role: lead

NCT04684446Phase 1Completed

Study in Adults of AZD1222 and rAd26-S Administered as Heterologous Prime-Boost Regimen for the Prevention of COVID-19

Role: lead