Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 90/100

Failure Rate

47.8%

11 terminated/withdrawn out of 23 trials

Success Rate

42.1%

-44.4% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

63%

5 of 8 completed trials have results

Key Signals

5 with results8 terminated

Enrollment Performance

Analytics

Phase 1
18(81.8%)
Phase 2
4(18.2%)
22Total
Phase 1(18)
Phase 2(4)

Activity Timeline

Global Presence

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Clinical Trials (23)

Showing 20 of 23 trials
NCT01827761Completed

Assessment of the Effectiveness of Chemotherapy Teaching: BrUOG 258

Role: collaborator

NCT00740181Phase 2Terminated

Decitabine, Cytarabine, GCSF for Refractory AML/MDS

Role: collaborator

NCT02850536Phase 1Completed

CAR-T Hepatic Artery Infusions or Pancreatic Venous Infusions for CEA-Expressing Liver Metastases or Pancreas Cancer

Role: lead

NCT04270929Phase 1Withdrawn

Pressure Enabled Drug Delivery By Pancreatic Retrograde Venous Infusion For Advanced Pancreatic Carcinoma

Role: lead

NCT01212627Phase 1Terminated

Ridaforolimus With Cetuximab: Adv Non-Small Cell Lung, Colorectal, Head & Neck Cancer

Role: collaborator

NCT00717756Phase 2Completed

Lenalidomide for Advanced Hepatocellular Cancer:A Phase II Trial

Role: collaborator

NCT01057277Phase 1Terminated

RAD001, Cisplatin and Concurrent Radiation for Locally Advanced, Inoperable Head and Neck Cancer

Role: collaborator

NCT01365130Phase 2Terminated

Chemotherapy for Patients With Gastroesophageal Cancers Who Have Progressed After One Prior Chemo Regimen

Role: collaborator

NCT02416466Phase 1Completed

CAR-T Hepatic Artery Infusions and Sir-Spheres for Liver Metastases

Role: lead

NCT01751282Phase 1Terminated

Study of the Effectiveness of Autologous Bone Marrow-Derived Mesenchymal Stem Cells in Fibrin to Treat Chronic Wounds

Role: lead

NCT00664196Phase 1Suspended

Trial of Anti-PSMA Designer T Cells in Advanced Prostate Cancer After Non-Myeloablative Conditioning

Role: lead

NCT00673829Phase 1Suspended

Trial of 2nd Generation Anti-CEA Designer T Cells in Metastatic Breast Cancer

Role: lead

NCT01929239Phase 1Suspended

Trial of Anti-PSMA Designer T Cells in Advanced Prostate Cancer After Non-Myeloablative Conditioning

Role: lead

NCT00673322Phase 1Terminated

Trial of Second Generation Designer T Cells in Colorectal Carcinoma

Role: lead

NCT01723306Phase 2Suspended

Phase II/Pilot Study of 2nd Generation Anti-CEA Designer T Cells in Adenocarcinomas

Role: lead

NCT00022230Phase 1Withdrawn

Combination Chemotherapy Plus Biological Therapy in Treating Patients With Stage II or Stage III Breast Cancer

Role: lead

NCT01081808Phase 1Terminated

Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors

Role: lead

NCT00569296Phase 1Terminated

Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and GM-CSF in Treating Patients With Recurrent, Refractory, or Metastatic Non-Small Cell Lung Cancer

Role: lead

NCT00007280Phase 1Completed

Bioengineered Skin and Wound Healing

Role: lead

NCT01373047Phase 1Completed

CEA-Expressing Liver Metastases Safety Study of Intrahepatic Infusions of Anti-CEA Designer T Cells

Role: lead