Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

29.4%

5 terminated/withdrawn out of 17 trials

Success Rate

68.8%

-17.8% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

73%

8 of 11 completed trials have results

Key Signals

1 recruiting8 with results

Enrollment Performance

Analytics

Phase 1
11(64.7%)
Phase 2
6(35.3%)
17Total
Phase 1(11)
Phase 2(6)

Activity Timeline

Global Presence

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Clinical Trials (17)

Showing 17 of 17 trials
NCT06189209Phase 2Recruiting

Efficacy and Safety of Tenalisib in Patients With Metastatic Triple Negative Breast Cancer (TNBC)

Role: lead

NCT05002868Phase 1Completed

Safety, Pharmacokinetics and Anti-tumor Activity of RP12146, in Patients With Solid Tumors

Role: lead

NCT05021900Phase 2Completed

Efficacy and Safety of Tenalisib (RP6530), in Patients With Locally Advanced or Metastatic Breast Cancer

Role: lead

NCT04204057Phase 2Completed

Efficacy and Safety of Tenalisib (RP6530) in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

Role: lead

NCT03711604Phase 1Completed

Compassionate Use Study of Tenalisib (RP6530)

Role: lead

NCT05246384Phase 1Withdrawn

Study to Evaluate the Safety, Pharmacokinetics and Clinical Activity of RP7214 in Combination With Azacitidine in Patients With Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia and Acute Myeloid Leukemia

Role: lead

NCT03770000Phase 1Completed

Safety and Efficacy of Tenalisib (RP6530) in Combination With Romidepsin in Patients With Relapsed/Refractory T-cell Lymphoma

Role: lead

NCT05239910Phase 2Withdrawn

Study to Evaluate the Efficacy and Safety of Tenalisib, Given With CHOP Therapy for Front Line Treatment in Patients With PTCL

Role: lead

NCT05007236Phase 2Completed

Study to Evaluate the Efficacy and Safety of Oral RP7214, a DHODH Inhibitor, in Patients With Symptomatic Mild COVID-19 Infection.

Role: lead

NCT04680429Phase 1Completed

A Single and Multiple Ascending and Food Effect Study of RP7214, a DHODH Inhibitor in Healthy Adult Subjects

Role: lead

NCT03711578Phase 2Completed

Efficacy and Safety Study of Tenalisib (RP6530), a Novel PI3K δ/γ Dual Inhibitor in Patients With Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma (iNHL)

Role: lead

NCT02567656Phase 1Completed

Safety and Efficacy Study of a Dual PI3K Delta/Gamma Inhibitor in T-cell Lymphoma

Role: lead

NCT03119467Phase 1Terminated

Safety and Efficacy Study of RP4010, in Patients With Relapsed or Refractory Lymphomas

Role: lead

NCT03471351Phase 1Terminated

Safety and Efficacy Study of Tenalisib (RP6530) in Combination With Pembrolizumab in Relapsed or Refractory cHL

Role: lead

NCT02958982Phase 1Terminated

Safety, Tolerability and Pharmacokinetics of Oral Doses of RP3128 of Rhizen Pharmaceuticals

Role: lead

NCT02690727Phase 1Completed

To Evaluate the Food Effect on Relative Bioavailability of RP6530 in Healthy Volunteers

Role: lead

NCT02017613Phase 1Completed

Safety and Efficacy Study of a Dual PI3K Delta/Gamma Inhibitor in Hematological Malignancies

Role: lead

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